García-Martínez Ana, García-Rosa Sergio, Gil-Rodrigo Adriana, Machado Victoria Torres, Pérez-Fonseca Carmen, Nickel Christian H, Artajona Lourdes, Jacob Javier, Llorens Pere, Herrero Pablo, Canadell Naila, Rangel Carolina, Martín-Sánchez Francisco Javier, Del Nogal Monserrat Lázaro, Miró Òscar
Emergency Department, IDIBAPS, Hospital Clínic, University of Barcelona, Villarroel, 170, 08036, Barcelona, Spain.
Emergency Department, Hospital Clínico San Carlos, Madrid, Spain.
Eur Geriatr Med. 2024 Oct;15(5):1281-1289. doi: 10.1007/s41999-024-00992-1. Epub 2024 May 29.
Fear of falling (FOF) may result in activity restriction and deconditioning. The aim of the study was to identify factors associated with FOF in older patients and to investigate if FOF influenced long-term outcomes.
Multicentric, observational, prospective study including patients 65 years or older attending the emergency department (ED) after a fall. Demographical, patient- and fall-related features were recorded at the ED. FOF was assessed using a single question. The primary outcome was all-cause death. Secondary outcomes included new fall-related visit, fall-related hospitalisation, and admission to residential care. Logistic regression and Cox regression models were used for statistical analyses.
Overall, 1464 patients were included (47.1% with FOF), followed for a median of 6.2 years (2.2-7.9). Seven variables (age, female sex, living alone, previous falls, sedative medications, urinary incontinence, and intrinsic cause of the fall) were directly associated with FOF whereas use of walking aids and living in residential care were inversely associated. After the index episode, 748 patients (51%) died (median 3.2 years), 677 (46.2%) had a new fall-related ED visit (median 1.7 years), 251 (17.1%) were hospitalised (median 2.8 years), and 197 (19.4%) were admitted to care (median 2.1 years). FOF was associated with death (HR 1.239, 95% CI 1.073-1.431), hospitalisation (HR 1.407, 95% CI 1.097-1.806) and institutionalisation (HR 1.578, 95% CI 1.192-2.088), but significance was lost after adjustment.
FOF is a prevalent condition in older patients presenting to the ED after a fall. However, it was not associated with long-term outcomes. Future research is needed to understand the influence of FOF in maintenance of functional capacity or quality of life.
害怕跌倒(FOF)可能导致活动受限和身体机能下降。本研究的目的是确定老年患者中与FOF相关的因素,并调查FOF是否会影响长期预后。
这是一项多中心、观察性、前瞻性研究,纳入65岁及以上因跌倒到急诊科(ED)就诊的患者。在急诊科记录人口统计学、患者及跌倒相关特征。使用单一问题评估FOF。主要结局是全因死亡。次要结局包括与跌倒相关的新就诊、与跌倒相关的住院治疗以及入住养老院。采用逻辑回归和Cox回归模型进行统计分析。
共纳入1464例患者(47.1%存在FOF),中位随访6.2年(2.2 - 7.9年)。七个变量(年龄、女性、独居、既往跌倒史、镇静药物使用、尿失禁以及跌倒的内在原因)与FOF直接相关,而使用助行器和入住养老院与FOF呈负相关。在索引事件发生后,748例患者(51%)死亡(中位时间3.2年),677例(46.2%)因跌倒相关情况再次到急诊科就诊(中位时间1.7年),251例(17.1%)住院治疗(中位时间2.8年),197例(19.4%)入住养老院(中位时间2.1年)。FOF与死亡(风险比1.239,95%置信区间1.073 - 1.431)、住院治疗(风险比1.407,95%置信区间1.097 - 1.806)和入住养老院(风险比1.578,95%置信区间1.192 - 2.088)相关,但调整后相关性不再显著。
在跌倒后到急诊科就诊的老年患者中,FOF较为普遍。然而,它与长期预后无关。未来需要开展研究,以了解FOF对维持功能能力或生活质量的影响。