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曲安奈德注射液治疗颧部水肿

Triamcinolone Injection in the Treatment of Malar Edema.

作者信息

Barańska-Rybak Wioletta, Świerczewska Zuzanna, Lemiec Agnieszka, Walker Lee

机构信息

Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, Poland.

La Estetica Clinic, Płock, Poland.

出版信息

Dermatol Pract Concept. 2024 Apr 1;14(2):e2024117. doi: 10.5826/dpc.1402a117.

DOI:10.5826/dpc.1402a117
PMID:38810029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11136127/
Abstract

INTRODUCTION

Tear-through deformities can be a detectable sign of facial aging. Over recent years, minimally invasive procedures such as hyaluronic acid filler injections have been shown to be effective in improving this area. Malar edema is the accumulation of fluid over the malar eminence persisting for 1 month or more. Given its nature, the management remains problematic. The most commonly reported treatment modality is injection with hyaluronidase.

OBJECTIVES

To determine the safety and efficacy of triamcinolone injection in the treatment of malar edema.

METHODS

A total of 15 female patients with malar edema, with a mean age of 43.77 years, were treated with triamcinolone injections. The volume injected was chosen by the investigator. Prior to the triamcinolone injection, all patients had been treated with hyaluronidase, which turned out to be ineffective in all cases. Patients were asked to note all adverse effects.

RESULTS

Satisfactory results were achieved after a single treatment session for 14 patients and after two treatments for one patient. Overall, injections with triamcinolone were well tolerated and no adverse reactions were reported.

CONCLUSIONS

Injection with triamcinolone appears to be a safe and effective option for the management of malar edema following hyaluronic acid filler injection. Nevertheless, further research with larger patient groups is compulsory.

摘要

引言

泪沟畸形可能是面部衰老的一个可察觉迹象。近年来,诸如透明质酸填充剂注射等微创程序已被证明在改善该区域方面有效。颧部水肿是指颧突上的液体积聚持续1个月或更长时间。鉴于其性质,治疗仍然存在问题。最常报道的治疗方式是注射透明质酸酶。

目的

确定曲安奈德注射治疗颧部水肿的安全性和有效性。

方法

总共15名平均年龄为43.77岁的颧部水肿女性患者接受了曲安奈德注射治疗。注射量由研究者选择。在注射曲安奈德之前,所有患者均已接受透明质酸酶治疗,但结果在所有病例中均无效。要求患者记录所有不良反应。

结果

14名患者单次治疗后取得了满意的效果,1名患者经过两次治疗后取得满意效果。总体而言,曲安奈德注射耐受性良好,未报告不良反应。

结论

曲安奈德注射似乎是透明质酸填充剂注射后颧部水肿管理的一种安全有效的选择。然而,必须对更大的患者群体进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e97c/11136127/38029704022f/dp1402a117g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e97c/11136127/38029704022f/dp1402a117g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e97c/11136127/38029704022f/dp1402a117g001.jpg

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本文引用的文献

1
A Retrospective Review of the Safety and Efficacy of Low-dose Triamcinolone Mixed with Hyaluronic Acid Fillers to Reduce Post-injection Infraorbital Swelling.低剂量曲安奈德与透明质酸填充剂混合以减轻注射后眶下肿胀的安全性和有效性的回顾性研究
J Clin Aesthet Dermatol. 2022 Apr;15(4):13-19.
2
Infraorbital Hyaluronic Acid Filler: Common Aesthetic Side Effects With Treatment and Prevention Options.眶下透明质酸填充剂:治疗及预防常见美学副作用的方法
Aesthet Surg J Open Forum. 2022 Jan 15;4:ojac001. doi: 10.1093/asjof/ojac001. eCollection 2022.
3
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
曲安奈德皮损内注射治疗瘢痕疙瘩和增生性瘢痕的安全性及有效性:一项系统评价和荟萃分析
Burns. 2021 Aug;47(5):987-998. doi: 10.1016/j.burns.2021.02.013. Epub 2021 Feb 24.
4
Nonvascular Complications of Injectable Fillers-Prevention and Management.可注射填充剂的非血管并发症——预防与管理
Indian J Plast Surg. 2020 Dec;53(3):335-343. doi: 10.1055/s-0040-1721872. Epub 2020 Dec 24.
5
Dermatologist Use of Intralesional Triamcinolone in the Treatment of Acne.皮肤科医生使用曲安奈德皮损内注射治疗痤疮
J Clin Aesthet Dermatol. 2020 Dec;13(12):41-43. Epub 2020 Dec 1.
6
Efficacy of high-dose intralesional triamcinolone for hidradenitis suppurativa.高剂量皮损内曲安奈德治疗化脓性汗腺炎的疗效。
Int J Dermatol. 2021 Feb;60(2):217-221. doi: 10.1111/ijd.15124. Epub 2020 Aug 17.
7
Periocular hyaluronic acid fillers: applications, implications, complications.眼周透明质酸填充剂:应用、影响、并发症。
Curr Opin Ophthalmol. 2019 Sep;30(5):395-400. doi: 10.1097/ICU.0000000000000595.
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Granulomatous Reaction to Intralesional Kenalog (Triamcinolone) Injection in Acne: A Case Report.痤疮患者皮损内注射曲安奈德(康宁克通)后的肉芽肿反应:一例报告
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Filling the periorbital hollows with hyaluronic acid gel: Long-term review of outcomes and complications.眶周凹陷填充透明质酸凝胶:长期疗效和并发症观察。
J Cosmet Dermatol. 2018 Aug;17(4):611-616. doi: 10.1111/jocd.12452. Epub 2017 Nov 11.
10
Dermal filler-associated malar edema: Treatment of a persistent adverse effect.真皮填充剂相关的颧部水肿:一种持续性不良反应的治疗
Orbit. 2017 Dec;36(6):473-475. doi: 10.1080/01676830.2017.1337203. Epub 2017 Aug 24.