Greene F L, Hicks C, Eddy V, Davis C
Am Surg. 1985 Jan;51(1):58-60.
While mammography has become a routine method both for the screening and preoperative assessment of breast disease, the role of this modality, especially when compared with newer techniques of breast imaging, needs continued assessment. Recent advances using sonographic principles and diaphanography (light transillumination) must be compared with mammography to define specificity, sensitivity, and accuracy in assessing breast lesions. During a 16-month period between November 1982 and February 1984, 467 women with clinically apparent breast disease (symptoms or palpable lesions) were each studied using all three imaging techniques of mammography, sonomammography, and diaphanography. Of 168 women recommended for biopsy on the basis of these techniques, 84 women had histologic confirmation during this study period. Benign breast disease was diagnosed histologically in 38 women, while carcinoma was found in 46 patients. These techniques showed no significant differences in predicting benign or malignant disease when rates of sensitivity, accuracy, and specificity are computed. Diaphanography (lightscanning), allowed for consistently correct interpretation of cases proven to be histologically malignant and showed a false-negative rate comparable with x-ray mammography. We conclude that diaphanography is a sensitive indicator of both benign and malignant breast disease while serving as a reliable predictor of clinically apparent breast lesions without the potential problems of radiation exposure.
虽然乳房X线摄影已成为乳腺疾病筛查和术前评估的常规方法，但这种检查方式的作用，尤其是与更新的乳腺成像技术相比时，仍需要持续评估。必须将利用超声原理和透照法（光透照）的最新进展与乳房X线摄影进行比较，以确定在评估乳腺病变时的特异性、敏感性和准确性。在1982年11月至1984年2月的16个月期间，对467名有明显乳腺疾病临床症状（症状或可触及病变）的女性，分别使用乳房X线摄影、超声乳腺成像和透照法这三种成像技术进行了研究。在基于这些技术建议进行活检的168名女性中，有84名女性在此研究期间获得了组织学确诊。组织学诊断为良性乳腺疾病的有38名女性，而发现46名患者患有癌症。计算敏感性、准确性和特异性率时，这些技术在预测良性或恶性疾病方面没有显著差异。透照法（光扫描）能够对经组织学证实为恶性的病例做出始终正确的解读，并且显示出与X线乳房X线摄影相当的假阴性率。我们得出结论，透照法是乳腺良性和恶性疾病的敏感指标，同时是临床明显乳腺病变的可靠预测指标，且不存在辐射暴露的潜在问题。
