Department of Paediatrics, Lagos University Teaching Hospital & College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria.
Department of Paediatrics, Federal Medical Centre, Abeokuta, Ogun State, Nigeria.
BJOG. 2024 Aug;131 Suppl 3:30-41. doi: 10.1111/1471-0528.17869. Epub 2024 May 31.
To describe the incidence, and sociodemographic and clinical factors associated with preterm birth and perinatal mortality in Nigeria.
Secondary analysis of data collected through the Maternal Perinatal Database for Quality, Equity and Dignity (MPD-4-QED) Programme.
Data from births in 54 referral-level hospitals across Nigeria between 1 September 2019 and 31 August 2020.
A total of 69 698 births.
Multilevel modelling was used to determine the factors associated with preterm birth and perinatal mortality.
Preterm birth and preterm perinatal mortality.
Of 62 383 live births, 9547 were preterm (153 per 1000 live births). Maternal age (<20 years - adjusted odds ratio [aOR] 1.52, 95% CI 1.36-1.71; >35 years - aOR 1.23, 95% CI 1.16-1.30), no formal education (aOR 1.68, 95% CI 1.54-1.84), partner not gainfully employed (aOR 1.94, 95% CI 1.61-2.34) and no antenatal care (aOR 2.62, 95% CI 2.42-2.84) were associated with preterm births. Early neonatal mortality for preterm neonates was 47.2 per 1000 preterm live births (451/9547). Father's occupation (manual labour aOR 1.52, 95% CI 1.20-1.93), hypertensive disorders of pregnancy (aOR 1.37, 95% CI 1.02-1.83), no antenatal care (aOR 2.74, 95% CI 2.04-3.67), earlier gestation (28 to <32 weeks - aOR 2.94, 95% CI 2.15-4.10; 32 to <34 weeks - aOR 1.80, 95% CI 1.3-2.44) and birthweight <1000 g (aOR 21.35, 95% CI 12.54-36.33) were associated with preterm perinatal mortality.
Preterm birth and perinatal mortality in Nigeria are high. Efforts should be made to enhance access to quality health care during pregnancy, delivery and the neonatal period, and improve the parental socio-economic status.
描述尼日利亚早产和围产儿死亡的发生率，以及与之相关的社会人口学和临床因素。
对通过孕产妇围产数据库进行质量、公平和尊严（MPD-4-QED）计划收集的数据进行二次分析。
2019 年 9 月 1 日至 2020 年 8 月 31 日期间，尼日利亚 54 家转诊级医院的分娩数据。
共有 69698 例分娩。
使用多水平模型确定与早产和围产儿死亡相关的因素。
早产和早产围产儿死亡率。
在 62383 例活产中，有 9547 例早产（每 1000 例活产中有 153 例早产）。母亲年龄（<20 岁-调整后的优势比[aOR]1.52，95%置信区间[CI]1.36-1.71；>35 岁-aOR 1.23，95%CI 1.16-1.30）、未接受正规教育（aOR 1.68，95%CI 1.54-1.84）、伴侣无固定收入（aOR 1.94，95%CI 1.61-2.34）和无产前护理（aOR 2.62，95%CI 2.42-2.84）与早产有关。早产儿的早期新生儿死亡率为每 1000 例早产活产儿 47.2 例（451/9547）。父亲的职业（体力劳动者-aOR 1.52，95%CI 1.20-1.93）、妊娠高血压疾病（aOR 1.37，95%CI 1.02-1.83）、无产前护理（aOR 2.74，95%CI 2.04-3.67）、妊娠早期（28-<32 周-aOR 2.94，95%CI 2.15-4.10；32-<34 周-aOR 1.80，95%CI 1.3-2.44）和出生体重<1000 克（aOR 21.35，95%CI 12.54-36.33）与早产围产儿死亡相关。
尼日利亚的早产和围产儿死亡率很高。应努力增加怀孕期间、分娩期间和新生儿期获得优质医疗保健的机会，并改善父母的社会经济地位。
