Zhou ShuJing, Wan Jing, Zou Jianmei, Zhang Yulan, He Huijun, Li Wei, Hu Jiale, Nie Jinfang, Yuan Yali, Zhang Yun
College of Chemistry and Bioengineering, Guilin University of Technology Guilin 541004 P. R. China
Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology Guilin 541004 China.
RSC Adv. 2024 May 30;14(25):17491-17497. doi: 10.1039/d4ra02340d. eCollection 2024 May 28.
A dual-signal optical sensing platform was successfully developed for the determination of ascorbic acid (AA) based on blue fluorescent carbon dots (CDs) and manganese dioxide nanosheets (MnO NSs) with strong Tyndall effect (TE) scattering and fluorescence quenching capabilities. In this nanosystem, CDs-MnO NS composites were employed as probes to evaluate the AA concentration. Owing to the strong reduction, the presence of the target AA could reduce the MnO NSs to Mn and induce the degradation of the MnO NSs, resulting in a significant decrease in the TE scattering intensity of the MnO NSs and the fluorescence recovery of the CDs. Therefore, a novel optical sensor based on TE scattering and fluorescence dual detectors was developed for the sensitive determination of AA. Under optimized conditions, the limits of detection (LODs) of the two modes were 113 and 3 nM, respectively. Furthermore, the dual-signal optical sensing platform was successfully applied for the detection of AA in human serum.
基于具有强廷德尔效应（TE）散射和荧光猝灭能力的蓝色荧光碳点（CDs）和二氧化锰纳米片（MnO NSs），成功开发了一种用于测定抗坏血酸（AA）的双信号光学传感平台。在这个纳米系统中，CDs-MnO NS复合材料被用作探针来评估AA浓度。由于强还原性，目标AA的存在可将MnO NSs还原为Mn并诱导MnO NSs降解，导致MnO NSs的TE散射强度显著降低以及CDs的荧光恢复。因此，开发了一种基于TE散射和荧光双探测器的新型光学传感器用于AA的灵敏测定。在优化条件下，两种模式的检测限（LOD）分别为113和3 nM。此外，该双信号光学传感平台成功应用于人血清中AA的检测。
