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Cutaneous T-cell lymphoma and dupilumab use: A retrospective matched cohort study of clinical characteristics and treatment outcomes.皮肤T细胞淋巴瘤与度普利尤单抗的使用：一项关于临床特征和治疗结果的回顾性匹配队列研究。
J Eur Acad Dermatol Venereol. 2025 Feb;39(2):e114-e117. doi: 10.1111/jdv.20141. Epub 2024 May 31.
2
Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: A retrospective cohort study.度普利尤单抗治疗特应性皮炎与皮肤 T 细胞淋巴瘤风险增加相关：一项回顾性队列研究。
J Am Acad Dermatol. 2024 Aug;91(2):255-258. doi: 10.1016/j.jaad.2024.03.039. Epub 2024 Apr 6.
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Cutaneous T-cell Lymphoma Progression: A Potential Dupilumab Pitfall.皮肤T细胞淋巴瘤进展：度普利尤单抗的一个潜在陷阱。
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Discordant lymphomas of classic Hodgkin lymphoma and peripheral T-cell lymphoma following dupilumab treatment for atopic dermatitis.特应性皮炎患者接受度普利尤单抗治疗后出现经典霍奇金淋巴瘤和外周 T 细胞淋巴瘤的不典型淋巴瘤。
Int J Hematol. 2022 Sep;116(3):446-452. doi: 10.1007/s12185-022-03330-y. Epub 2022 Mar 30.
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J Am Acad Dermatol. 2025 Feb;92(2):e41-e42. doi: 10.1016/j.jaad.2024.08.082. Epub 2024 Sep 30.
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Increased Risk of Cutaneous T-Cell Lymphoma Development after Dupilumab Use for Atopic Dermatitis.使用度普利尤单抗治疗特应性皮炎后皮肤T细胞淋巴瘤发生风险增加。
Dermatol Ther. 2024 Jan;2024. doi: 10.1155/2024/9924306. Epub 2024 Aug 14.
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Response to Flynn et al, "Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: A retrospective cohort study".
J Am Acad Dermatol. 2025 Jan;92(1):e7-e8. doi: 10.1016/j.jaad.2024.08.031. Epub 2024 Aug 30.
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Response to Shih et al. "Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: A retrospective cohort study".
J Am Acad Dermatol. 2024 Nov;91(5):e139-e140. doi: 10.1016/j.jaad.2024.07.009. Epub 2024 Jul 11.
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Response to Hasan et al's "Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T cell lymphoma: A retrospective cohort study".
J Am Acad Dermatol. 2024 Nov;91(5):e145-e146. doi: 10.1016/j.jaad.2024.06.091. Epub 2024 Jul 20.
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Response to Hasan et al., "Dupilumab therapy for atopic dermatitis is associated with increased risk of cutaneous T-cell lymphoma: A retrospective cohort study".
J Am Acad Dermatol. 2025 Jan;92(1):e9-e10. doi: 10.1016/j.jaad.2024.06.105. Epub 2024 Aug 24.

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Drug- and Vaccine-Induced Cutaneous T-Cell Lymphoma: A Systematic Review of the Literature.药物和疫苗诱导的皮肤T细胞淋巴瘤：文献系统评价
J Skin Cancer. 2025 Feb 27;2025:3103865. doi: 10.1155/jskc/3103865. eCollection 2025.

本文引用的文献

1
Detecting T-cell receptor clonality in patients with severe atopic dermatitis refractory to dupilumab.检测对度普利尤单抗难治的重度特应性皮炎患者的 T 细胞受体克隆性。
J Eur Acad Dermatol Venereol. 2024 Oct;38(10):1939-1946. doi: 10.1111/jdv.20053. Epub 2024 Apr 30.
2
Dupilumab-Associated Lymphoid Reactions in Patients With Atopic Dermatitis.特应性皮炎患者中与度普利尤单抗相关的淋巴反应。
JAMA Dermatol. 2023 Nov 1;159(11):1240-1247. doi: 10.1001/jamadermatol.2023.3849.
3
Dupilumab-associated mycosis fungoides: a cross-sectional study.达必妥相关蕈样肉芽肿：一项横断面研究。
Arch Dermatol Res. 2023 Nov;315(9):2561-2569. doi: 10.1007/s00403-023-02652-z. Epub 2023 Jun 4.
4
Unmasking a masquerader: Mycosis fungoides unveiled after dupilumab treatment.揭开伪装者的面纱：度普利尤单抗治疗后揭示蕈样肉芽肿
J Am Acad Dermatol. 2023 Jun;88(6):e305-e306. doi: 10.1016/j.jaad.2023.01.047. Epub 2023 Feb 28.
5
Diagnosis of mycosis fungoides or Sézary syndrome after dupilumab use: A systematic review.使用度普利尤单抗后蕈样肉芽肿或塞扎里综合征的诊断：一项系统评价
J Am Acad Dermatol. 2023 May;88(5):1164-1166. doi: 10.1016/j.jaad.2022.12.001. Epub 2022 Dec 5.
6
Evolution of Dupilumab-Associated Cutaneous Atypical Lymphoid Infiltrates.度匹鲁单抗相关皮肤非典型淋巴样浸润的演变。
Am J Dermatopathol. 2021 Oct 1;43(10):714-720. doi: 10.1097/DAD.0000000000001875.
7
Acceleration of cutaneous T-cell lymphoma following dupilumab administration.使用度普利尤单抗后皮肤T细胞淋巴瘤加速进展。
JAAD Case Rep. 2020 Dec 17;8:83-85. doi: 10.1016/j.jdcr.2020.12.010. eCollection 2021 Feb.
8
Mycosis Fungoides Unmasked by Dupilumab Treatment in a Patient With a History of Atopic Dermatitis.度普利尤单抗治疗一名有特应性皮炎病史患者后暴发性蕈样肉芽肿
Dermatitis. 2021 Oct 1;32(1S):e88-e89. doi: 10.1097/DER.0000000000000679.
9
Long-standing dermatitis treated with dupilumab with subsequent progression to cutaneous T-cell lymphoma.长期存在的皮炎用度普利尤单抗治疗后进展为皮肤 T 细胞淋巴瘤。
Cutis. 2020 Aug;106(2):E8-E11. doi: 10.12788/cutis.0074.
10
Progression of cutaneous T-cell lymphoma after dupilumab: Case review of 7 patients.度普利尤单抗治疗后皮肤T细胞淋巴瘤进展：7例患者病例回顾
J Am Acad Dermatol. 2020 Jul;83(1):197-199. doi: 10.1016/j.jaad.2020.03.050. Epub 2020 Mar 27.

Cutaneous T-cell lymphoma and dupilumab use: A retrospective matched cohort study of clinical characteristics and treatment outcomes.

作者信息

Stuver Robert, Dusza Stephen, Epstein-Peterson Zachary D, Ghione Paola, Horwitz Steven M, Johnson William, Moskowitz Alison J, Myskowski Patricia, Pulitzer Melissa, Geller Shamir

机构信息

Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.

出版信息

J Eur Acad Dermatol Venereol. 2025 Feb;39(2):e114-e117. doi: 10.1111/jdv.20141. Epub 2024 May 31.

DOI:10.1111/jdv.20141
PMID:38818876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11607143/
Abstract
摘要