Pan African University Institute for Basic Sciences, Technology and Innovation, Nairobi, Kenya.
Haramaya University, Dire Dawa, Ethiopia.
PLoS One. 2024 May 31;19(5):e0303637. doi: 10.1371/journal.pone.0303637. eCollection 2024.
Low birth weight is a significant risk factor associated with high rates of neonatal and infant mortality, particularly in developing countries. However, most studies conducted on this topic in Ethiopia have small sample sizes, often focusing on specific areas and using standard models employing maximum likelihood estimation, leading to potential bias and inaccurate coverage probability.
This study used a novel approach, the Bayesian rank likelihood method, within a latent traits model, to estimate parameters and provide a nationwide estimate of low birth weight and its risk factors in Ethiopia. Data from the Ethiopian Demographic and Health Survey (EDHS) of 2016 were used as a data source for the study. Data stratified all regions into urban and rural areas. Among 15, 680 representative selected households, the analysis included complete cases from 10, 641 children (0-59 months). The evaluation of model performance considered metrics such as the root mean square error, the mean absolute error, and the probability coverage of the corresponding 95% confidence intervals of the estimates.
Based on the values of root mean square error, mean absolute error, and probability coverage, the estimates obtained from the proposed model outperform the classical estimates. According to the result, 40.92% of the children were born with low birth weight. The study also found that low birth weight is unevenly distributed across different regions of the country with the highest amounts of variation observed in the Afar, Somali and Southern Nations, Nationalities, and Peoples regions as represented by the latent trait parameter of the model. In contrast, the lowest low birth weight variation was recorded in the Addis Ababa, Dire Dawa, and Amhara regions. Furthermore, there were significant associations between birth weight and several factors, including the age of the mother, number of antenatal care visits, order of birth and the body mass index as indicated by the average posterior beta values of (β1= -0.269, CI=-0.320, -0.220), (β2= -0.235, CI=-0.268, -0.202), (β3= -0.120, CI=-0.162, -0.074) and (β5= -0.257, CI=-0.291, -0.225).
The study showed that the low birth weight estimates obtained from the latent trait model outperform the classical estimates. The study also revealed that the prevalence of low birth weight varies between different regions of the country, indicating the need for targeted interventions in areas with a higher prevalence. To effectively reduce the prevalence of low birth weight and improve maternal and child health outcomes, it is important to concentrate efforts on regions with a higher burden of low birth weight. This will help implement interventions that are tailored to the unique challenges and needs of each area. Health institutions should take measures to reduce low birth weight, with a special focus on the factors identified in this study.
低出生体重是与新生儿和婴儿死亡率高相关的重要风险因素,尤其是在发展中国家。然而,在埃塞俄比亚进行的大多数关于这个主题的研究样本量较小,通常集中在特定的地区,并使用最大似然估计的标准模型,这可能导致潜在的偏差和不准确的覆盖概率。
本研究使用了一种新的方法,即在潜在特征模型中使用贝叶斯等级似然法,来估计参数并提供埃塞俄比亚全国范围内低出生体重及其危险因素的估计值。该研究使用了 2016 年埃塞俄比亚人口与健康调查(EDHS)的数据作为数据源。数据将所有地区分为城市和农村地区。在 15680 个有代表性的选定家庭中,分析包括来自 10641 名(0-59 个月)儿童的完整案例。模型性能的评估考虑了均方根误差、平均绝对误差和对应估计值的 95%置信区间的概率覆盖等指标。
根据均方根误差、平均绝对误差和概率覆盖的数值,与经典估计相比,提出的模型得到的估计值表现更好。根据研究结果,40.92%的儿童出生体重较低。该研究还发现,低出生体重在全国不同地区的分布不均,模型中潜在特征参数所代表的国家,奥罗米亚、索马里和南方各族州、民族和人民地区的变异量最大。相比之下,在亚的斯亚贝巴、德雷达瓦和阿姆哈拉地区,低出生体重的变异量最低。此外,出生体重与母亲年龄、产前护理就诊次数、分娩顺序和体重指数等因素之间存在显著关联,这一点由(β1=-0.269,CI=-0.320,-0.220)、(β2=-0.235,CI=-0.268,-0.202)、(β3=-0.120,CI=-0.162,-0.074)和(β5=-0.257,CI=-0.291,-0.225)的平均后验β 值表示。
研究表明,潜在特征模型得到的低出生体重估计值优于经典估计值。该研究还表明,低出生体重的流行率在全国不同地区有所不同,这表明需要在流行率较高的地区采取有针对性的干预措施。为了有效降低低出生体重的流行率,改善母婴健康结果,重要的是要集中精力在低出生体重负担较重的地区。这将有助于实施针对每个地区独特挑战和需求的干预措施。卫生机构应采取措施降低低出生体重,特别关注本研究确定的因素。