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随着时间的推移,通过自我报告和磷脂酰乙醇胺 16:0/18:1 评估老年人的饮酒流行率和变化-亨于尔研究。

Prevalence and change in alcohol consumption in older adults over time, assessed with self-report and Phosphatidylethanol 16:0/18:1 -The HUNT Study.

机构信息

Norwegian National Centre for Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway.

Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

出版信息

PLoS One. 2024 May 31;19(5):e0304714. doi: 10.1371/journal.pone.0304714. eCollection 2024.

Abstract

BACKGROUND

Changes in alcohol consumption may affect older adults' health. We examined prevalence and changes in the alcohol consumption of older women and men (≥65 years) in Norway over a 24-year period.

METHODS

Data from three population-based health surveys (The Trøndelag Health Study-HUNT2 1995-97, HUNT3 2006-08, HUNT4 2017-19) were used. Alcohol consumption was measured using self-reported measures and an objective measure of alcohol consumption (Phosphatidylethanol 16:0/18:1, PEth). Self-reported lifetime abstinence, former drinking, current drinking, frequent drinking (≥4 times/week), and risk drinking (≥8 units/week) were measured. The PEth concentrations were stratified: <0.03 μmol/l (abstinence/very low level of alcohol consumption); >0.06 μmol/l (indicating >1 unit/day); >0.10 μmol/l (indicating >3 units/day), and >0.30 μmol/l (heavy alcohol consumption).

RESULTS

In HUNT4, the prevalence of self-reported lifetime abstinence, frequent drinking, and risk drinking was 5.2%, 4.4%, and 5.6%, respectively, while prevalence of PEth <0.03 μmol/l was 68.1% and PEth >0.06 μmol/l was 21.2%. Over the course of the three surveys, the prevalence of self-reported lifetime abstinence decreased, while the prevalence of frequent drinking and risk drinking increased. Men were less often abstainers and more often frequent and risky drinkers than women in all three surveys. Gender differences for abstinence and current drinking reduced with time. From HUNT3 to HUNT4, the prevalence of PEth <0.03 μmol/l decreased, while the prevalence of PEth >0.06 μmol/l increased. Men compared to women, had less often PEth <0.03 μmol/l and more often PEth >0.06 and >0.10 μmol/l in HUNT3 and HUNT4. Women and men ≥75 years were just as likely to have PEth >0.30 μmol/l in HUNT4. The gender differences in PEth concentrations were reduced in HUNT4 among those aged 70-74 years or ≥75 years.

CONCLUSION

Alcohol consumption has increased among Norwegian older adults over a 24-year period, but at a slower pace during the last decade.

摘要

背景

饮酒习惯的改变可能会影响老年人的健康。我们调查了 24 年来挪威老年女性和男性(≥65 岁)的饮酒频率和变化情况。

方法

使用了三项基于人群的健康调查(1995-97 年的特隆赫姆健康研究-HUNT2、2006-08 年的 HUNT3、2017-19 年的 HUNT4)的数据。使用自我报告的测量和一种客观的酒精摄入量测量方法(磷脂酰乙醇 16:0/18:1,PEth)来测量饮酒量。测量了终身戒酒、曾经饮酒、当前饮酒、频繁饮酒(≥每周 4 次)和风险饮酒(≥每周 8 单位)。PEth 浓度分层为:<0.03 μmol/l(戒酒/低水平饮酒);>0.06 μmol/l(表示每日饮酒 1 单位以上);>0.10 μmol/l(表示每日饮酒 3 单位以上)和>0.30 μmol/l(大量饮酒)。

结果

在 HUNT4 中,自我报告的终身戒酒、频繁饮酒和风险饮酒的患病率分别为 5.2%、4.4%和 5.6%,而 PEth <0.03 μmol/l 的患病率为 68.1%,PEth >0.06 μmol/l 的患病率为 21.2%。在三次调查过程中,自我报告的终身戒酒率下降,而频繁饮酒和风险饮酒的比例增加。与女性相比,男性在所有三次调查中更不易戒酒,更频繁饮酒和更易风险饮酒。随着时间的推移,男女之间的戒酒和当前饮酒的差异有所缩小。从 HUNT3 到 HUNT4,PEth <0.03 μmol/l 的患病率下降,而 PEth >0.06 μmol/l 的患病率增加。与女性相比,男性在 HUNT3 和 HUNT4 中更不易有 PEth <0.03 μmol/l,而更易有 PEth >0.06 和 >0.10 μmol/l。在 HUNT4 中,75 岁及以上的女性和男性同样更有可能有 PEth >0.30 μmol/l。在 70-74 岁或 75 岁及以上的人群中,HUNT4 中的性别差异在 PEth 浓度方面有所缩小。

结论

在 24 年的时间里,挪威老年人的饮酒量有所增加,但在过去十年中增长速度有所放缓。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7876/11142565/469c81d48553/pone.0304714.g001.jpg

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