Berg Mark T, Riley Kendall, Lei Man-Kit, Simons Ronald L
Department of Sociology and Criminology, University of Iowa, Iowa City, IA, USA.
Department of Sociology, University of Georgia, Athens, Georgia.
J Aging Health. 2024 May 31:8982643241257065. doi: 10.1177/08982643241257065.
The study draws upon perspectives on life-course stressors and health to assess whether lifetime incarceration exposure is a determinant of biological aging and self-reported depression. Using data from a sample of 460 African American participants (average age= 57) in the Family and Community Health Study, the study examined two epigenetic indices of biological aging, DunedinPoAm and GrimAge, as well as a self-reported measure of depression symptoms. Estimates were derived from multivariate regression models with adjustments for selection on observables and confounding factors. Exposure to incarceration was a significant determinant of accelerated biological aging (GrimAge) and the pace of aging (DunedinPoAm) and depressive symptoms. Among formerly incarcerated older adults, past experiences with the stressors of incarceration predict key biomarkers of physiological deterioration and depressive symptoms. Incarceration contributes to the mental and physical health burden of older adults.
该研究借鉴了关于生命历程应激源与健康的观点，以评估终身监禁经历是否是生物衰老和自我报告的抑郁的一个决定因素。利用家庭与社区健康研究中460名非裔美国参与者（平均年龄 = 57岁）样本的数据，该研究考察了生物衰老的两个表观遗传指标，即达尼丁多组学加速衰老（DunedinPoAm）和格里姆年龄（GrimAge），以及抑郁症状的自我报告测量。估计值来自对可观测因素和混杂因素进行调整的多元回归模型。监禁经历是加速生物衰老（GrimAge）、衰老速度（DunedinPoAm）和抑郁症状的一个重要决定因素。在曾经被监禁的老年人中，过去监禁应激源的经历可预测生理衰退和抑郁症状的关键生物标志物。监禁加重了老年人的身心健康负担。
