The London Breast Institute, The Princess Grace Hospital, London, U.K.
College of Medicine and Health, University of Exeter Medical School, Exeter, U.K.
Anticancer Res. 2024 Jun;44(6):2287-2295. doi: 10.21873/anticanres.17036.
Breast cancer remains a global health challenge, prompting a search for preventive strategies beyond conventional approaches. This review explores the potential of specific micronutrients, including antioxidants, vitamins, and probiotics, in breast cancer prevention. Through an extensive literature search encompassing PubMed up to March 2024, 14 micronutrients emerged with promising roles in breast cancer prevention. These include five vitamins: folate, vitamin D, vitamin B6, beta carotene, and vitamin C and nine other micronutrients: curcumin, piperine, epigallocatechin-3-gallate, quercetin, sulforaphane, indole-3-carbinol, lactobacillus, n-3 polyunsaturated fatty acids and lycopene. Understanding the efficacy of these micronutrients could pave the way for personalized preventive interventions, offering new avenues for reducing breast cancer incidence and improving public health outcomes.
乳腺癌仍然是一个全球性的健康挑战，促使人们寻求超越传统方法的预防策略。本综述探讨了特定微量营养素（包括抗氧化剂、维生素和益生菌）在乳腺癌预防中的潜力。通过对截至 2024 年 3 月的 PubMed 进行广泛的文献检索，有 14 种微量营养素在乳腺癌预防中具有有前景的作用。其中包括五种维生素：叶酸、维生素 D、维生素 B6、β-胡萝卜素和维生素 C，以及其他九种微量营养素：姜黄素、胡椒碱、表没食子儿茶素-3-没食子酸酯、槲皮素、萝卜硫素、吲哚-3-甲醇、乳杆菌、n-3 多不饱和脂肪酸和番茄红素。了解这些微量营养素的功效可以为个性化预防干预铺平道路，为降低乳腺癌发病率和改善公共健康结果提供新途径。
