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霍奇金淋巴瘤

Hodgkin's disease.

作者信息

Desforges J F, Rutherford C J, Piro A

出版信息

N Engl J Med. 1979 Nov 29;301(22):1212-22. doi: 10.1056/NEJM197911293012205.

Abstract

During the past two decades, new approaches to the diagnosis and treatment of Hodgkin's disease have contributed to improved rates of survival and probable cure. Currently, patients with Hodgkin's disease are treated according to the stage and symptoms of their disease. The degree of certainty necessary for determining stage depends on the potential effectiveness of the therapeutic options available in a given case. Certain cases have been identified where treatment with a single modality has been disappointing, and the use of both radiotherapy and chemotherapy may be considered for these. Such decisions can be made only by evaluating the effectiveness of salvage after relapse following single-modality treatment and assessing the added hazards of initial treatment with both modalities.

摘要

在过去二十年中,霍奇金淋巴瘤的诊断和治疗新方法提高了生存率并有望实现治愈。目前,霍奇金淋巴瘤患者根据疾病分期和症状进行治疗。确定分期所需的确定程度取决于特定病例中可用治疗方案的潜在疗效。已发现某些病例采用单一治疗方式效果不佳,对于这些病例可考虑联合使用放疗和化疗。只有通过评估单一治疗方式复发后的挽救治疗效果以及评估两种治疗方式初始治疗的额外风险,才能做出此类决策。

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