Suppr超能文献

原发慢性 B 型主动脉夹层中孙氏手术的长期结果。

Long-term results of the frozen elephant trunk technique in primary chronic type B aortic dissection.

机构信息

Department of Thoracic and Cardiovascular Surgery, Mie University Hospital, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.

Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2024 Dec;72(12):770-778. doi: 10.1007/s11748-024-02043-9. Epub 2024 May 31.

Abstract

OBJECTIVES

The aim of this study is to analyze long-term results of the total aortic arch replacement with the frozen elephant trunk technique for primary chronic type B aortic dissection.

METHODS

Among 322 patients who had the frozen elephant trunk technique, 43 (13.4%) patients (median age, 64.0 years) with primary chronic type B aortic dissection were analyzed. The patients underwent surgery at a median of 27.0 months after the onset of aortic dissection. The false lumen was patent in 30 (69.8%) patients preoperatively.

RESULTS

Two patients suffered paraplegia and another died of cerebral infarction. Complete thrombosis of the peri-stent false lumen was achieved in 36 (83.7%) patients. Overall survival, freedom from aortic events, and freedom from aortic reintervention were 83.5%, 37.2%, and 42.2% at 5 years, respectively. Survival rates of the patients with or without aortic events were 75.0% and 95.8% at 5 years (Log-rank, p = 0.22). Late aortic events occurred in 19 (44.2%) patients including distal stent graft-induced new entry, type Ib endoleak, and false lumen dilation. The ratio of the stent graft diameter to the preoperative short axis diameter of the true lumen (hazard ratio, 1.90; 95% confidence interval, 1.01-3.59), and the maximal diameter of a postdissection aneurysm (1.07; 1.01-1.12) were the significant multivariate risk predictors of late aortic events.

CONCLUSIONS

Late aortic events occurr fairly frequently, and new strategies need to be explored to enhance the effectiveness of this procedure in the future.

摘要

目的

本研究旨在分析应用冷冻象鼻技术行全主动脉弓置换术治疗原发性慢性 B 型主动脉夹层的长期结果。

方法

在 322 例行冷冻象鼻技术的患者中,分析了 43 例(13.4%)原发性慢性 B 型主动脉夹层患者(中位年龄 64.0 岁)。这些患者在主动脉夹层发病后中位 27.0 个月接受手术。30 例(69.8%)患者术前假腔仍通畅。

结果

2 例患者发生截瘫,另 1 例患者死于脑梗死。36 例(83.7%)患者支架内假腔完全血栓形成。5 年时总生存率、无主动脉事件生存率和无主动脉再次介入治疗生存率分别为 83.5%、37.2%和 42.2%。有和无主动脉事件的患者生存率分别为 75.0%和 95.8%(对数秩检验,p=0.22)。19 例(44.2%)患者发生晚期主动脉事件,包括远端支架移植物导致的新入口、Ib 型内漏和假腔扩张。支架移植物直径与术前真腔短轴直径的比值(危险比,1.90;95%置信区间,1.01-3.59)和夹层动脉瘤的最大直径(1.07;1.01-1.12)是晚期主动脉事件的显著多变量危险因素。

结论

晚期主动脉事件相当常见,未来需要探索新策略以提高该术式的效果。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验