• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人工唾液对口干控制的影响:COVID-19 患者接受无创机械通气的半实验研究。

The effect of artificial saliva on the control of dry mouth: a semi-experimental study on COVID-19 patients under Non-invasive mechanical ventilation.

机构信息

Department of Medical and Surgical Nursing, School of Nursing and Midwifery, Clinical Research Development Center, Shahid Modarres Educational hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Master of Critical Care Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

BMC Oral Health. 2024 May 31;24(1):643. doi: 10.1186/s12903-024-04386-4.

DOI:10.1186/s12903-024-04386-4
PMID:38822326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11140887/
Abstract

OBJECTIVES

Since maintaining oral hygiene is essential in nursing care, the present study was conducted to determine the effect of oral care using Mucosamin artificial saliva spray to control dry mouth in ICU patients with COVID-19.

MATERIALS AND METHODS

The current semi-experimental research was conducted on eighty patients with COVID-19 selected using the available sampling method. The study tool was a Beck oral assessment scale (BOAS). The case and control groups were selected from two hospitals with relatively similar conditions and treatment procedures. For patients in the intervention group, mucosamin artificial saliva spray was used in addition to the common care, while control group patients received only common care.

RESULTS

Eighty patients were randomly assigned to two groups named control and intervention (40 patients in each group). The intervention was very effective in reducing the BOAS score after four days in comparison with the control group (9.23 vs. 12.05, respectively; p-value < 0.001). Based on the adjusted model, the application of artificial saliva reduced the BOAS score, indicating improvement in mouth dryness. While the BOAS score was increased in the control group, it had a declining trend in the intervention one.

CONCLUSION

The study's results showed that using artificial saliva spray could effectively reduce the symptoms of dry mouth in patients with COVID-19 treated with non-invasive mechanical ventilation.

CLINICAL RELEVANCE

The present study introduced an applicable solution (artificial saliva) to treat mouth dryness in ICU patients under mechanical ventilation.

摘要

目的

由于口腔卫生护理在护理中至关重要,本研究旨在确定使用 Mucosamin 人工唾液喷雾来控制 COVID-19 重症监护病房患者口干的效果。

材料与方法

本半实验研究共纳入 80 例 COVID-19 患者,采用方便抽样法进行选择。研究工具是 Beck 口腔评估量表(BOAS)。病例组和对照组是从两个具有相似条件和治疗程序的医院中选择的。对于干预组患者,除了常规护理外,还使用了 mucosamin 人工唾液喷雾,而对照组患者仅接受常规护理。

结果

80 名患者被随机分为两组,分别命名为对照组和干预组(每组 40 名患者)。与对照组相比,干预组在四天后 BOAS 评分显著降低(分别为 9.23 分和 12.05 分;p 值<0.001)。根据调整后的模型,人工唾液的应用降低了 BOAS 评分,表明口干症状有所改善。而对照组的 BOAS 评分增加,干预组则呈下降趋势。

结论

研究结果表明,使用人工唾液喷雾可以有效减轻 COVID-19 患者接受无创机械通气治疗时的口干症状。

临床相关性

本研究提出了一种可应用的解决方案(人工唾液)来治疗机械通气下 ICU 患者的口干问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/1261f44ab9a4/12903_2024_4386_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/1d5205283bca/12903_2024_4386_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/6f42e979618a/12903_2024_4386_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/1261f44ab9a4/12903_2024_4386_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/1d5205283bca/12903_2024_4386_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/6f42e979618a/12903_2024_4386_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11140887/1261f44ab9a4/12903_2024_4386_Fig3_HTML.jpg

相似文献

1
The effect of artificial saliva on the control of dry mouth: a semi-experimental study on COVID-19 patients under Non-invasive mechanical ventilation.人工唾液对口干控制的影响:COVID-19 患者接受无创机械通气的半实验研究。
BMC Oral Health. 2024 May 31;24(1):643. doi: 10.1186/s12903-024-04386-4.
2
Effects of carboxymethylcellulose (CMC)-based artificial saliva in patients with xerostomia.羧甲基纤维素(CMC)基人工唾液对口干症患者的影响。
Int J Oral Maxillofac Surg. 2008 Nov;37(11):1027-31. doi: 10.1016/j.ijom.2008.06.006. Epub 2008 Jul 21.
3
Interventions for the management of dry mouth: topical therapies.口干管理的干预措施:局部治疗
Cochrane Database Syst Rev. 2011 Dec 7(12):CD008934. doi: 10.1002/14651858.CD008934.pub2.
4
Clinical evaluation of a new artificial saliva in spray form for patients with dry mouth.一种新型喷雾型人工唾液用于口干患者的临床评估。
Med Oral Patol Oral Cir Bucal. 2009 Jan 1;14(1):E8-E11.
5
Clinical trial of a mucin-containing oral spray for treatment of xerostomia in hospice patients.含粘蛋白口腔喷雾剂治疗临终关怀患者口干症的临床试验。
Palliat Med. 1997 May;11(3):225-32. doi: 10.1177/026921639701100307.
6
Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial.COVID-19 住院成人患者使用伊马替尼的安全性和疗效:一项随机对照试验研究方案的结构化总结。
Trials. 2020 Oct 28;21(1):897. doi: 10.1186/s13063-020-04819-9.
7
Multi-centre, three arm, randomized controlled trial on the use of methylprednisolone and unfractionated heparin in critically ill ventilated patients with pneumonia from SARS-CoV-2 infection: A structured summary of a study protocol for a randomised controlled trial.多中心、三臂、随机对照试验研究甲泼尼龙和普通肝素在 SARS-CoV-2 感染肺炎危重症机械通气患者中的应用:一项随机对照试验研究方案的结构化总结。
Trials. 2020 Aug 17;21(1):724. doi: 10.1186/s13063-020-04645-z.
8
Efficacy of a new oral lubricant solution in the management of psychotropic drug-induced xerostomia: a randomized controlled trial.一种新型口腔润滑溶液治疗精神药物所致口干症的疗效:一项随机对照试验
J Clin Psychopharmacol. 2007 Oct;27(5):437-43. doi: 10.1097/jcp.0b013e31814db434.
9
Oral lesions and saliva alterations of COVID-19 patients in an intensive care unit: A retrospective study.COVID-19 患者在重症监护病房中的口腔病变和唾液改变:一项回顾性研究。
Spec Care Dentist. 2022 Sep;42(5):494-502. doi: 10.1111/scd.12705. Epub 2022 Mar 3.
10
Cohort of Four Thousand Four Hundred Four Persons Under Investigation for COVID-19 in a New York Hospital and Predictors of ICU Care and Ventilation.在纽约一家医院中对 4404 人进行的 COVID-19 调查队列研究,以及 ICU 护理和通气的预测因素。
Ann Emerg Med. 2020 Oct;76(4):394-404. doi: 10.1016/j.annemergmed.2020.05.011. Epub 2020 May 11.

引用本文的文献

1
Oral complications during the two waves of COVID-19 pandemic in China: a prospective cross-section analysis of 510 cases using questionnaire.中国两波 COVID-19 大流行期间的口腔并发症:使用问卷对 510 例病例进行前瞻性横断面分析。
BMC Oral Health. 2024 Oct 23;24(1):1265. doi: 10.1186/s12903-024-05058-z.

本文引用的文献

1
Non-invasive ventilation (NIV) induced bilateral subcutaneous emphysema in SARS COV-2 patient: A rare occurrence.无创通气(NIV)导致新冠病毒患者双侧皮下气肿:罕见病例。
Trends Anaesth Crit Care. 2021 Jun;38:18-20. doi: 10.1016/j.tacc.2021.03.008. Epub 2021 Mar 29.
2
Herpesviruses and SARS-CoV-2: Viral Association with Oral Inflammatory Diseases.疱疹病毒与严重急性呼吸综合征冠状病毒2:病毒与口腔炎性疾病的关联
Pathogens. 2024 Jan 7;13(1):58. doi: 10.3390/pathogens13010058.
3
Prevalence of oral complications in the course of severe SARS-CoV-2 infection under mechanical non-invasive ventilation.
严重 SARS-CoV-2 感染患者在接受机械无创通气治疗过程中口腔并发症的发生情况。
Eur J Med Res. 2023 Aug 22;28(1):293. doi: 10.1186/s40001-023-01273-6.
4
Impact of tooth brushing on oral bacteriota and health care-associated infections among ventilated COVID-19 patients: an intervention study.刷牙对 COVID-19 机械通气患者口腔细菌和与医疗保健相关感染的影响:一项干预研究。
Antimicrob Resist Infect Control. 2023 Mar 8;12(1):17. doi: 10.1186/s13756-023-01218-y.
5
Oral lesions and saliva alterations of COVID-19 patients in an intensive care unit: A retrospective study.COVID-19 患者在重症监护病房中的口腔病变和唾液改变:一项回顾性研究。
Spec Care Dentist. 2022 Sep;42(5):494-502. doi: 10.1111/scd.12705. Epub 2022 Mar 3.
6
Impact of a dental care intervention on the hospital mortality of critically ill patients admitted to intensive care units: A quasi-experimental study.口腔护理干预对入住重症监护病房的危重症患者住院死亡率的影响:一项准实验研究。
Am J Infect Control. 2022 Oct;50(10):1156-1161. doi: 10.1016/j.ajic.2022.01.022. Epub 2022 Jan 30.
7
Evaluation of Mucosamin Effect on Treating Radiation Induced Oral Mucositis during and after Radiotherapy amongst Patients with Oral Cavity Squamous Cell Carcinoma.评价口腔粘膜炎防治剂(Mucosamin)在口腔鳞癌放疗中及放疗后对放射性口腔黏膜炎的防治效果。
Asian Pac J Cancer Prev. 2021 Nov 1;22(11):3711-3715. doi: 10.31557/APJCP.2021.22.11.3711.
8
Anticholinergic medication: Related dry mouth and effects on the salivary glands.抗胆碱能药物:相关的口干和对唾液腺的影响。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Dec;132(6):662-670. doi: 10.1016/j.oooo.2021.08.015. Epub 2021 Aug 29.
9
Symptom management to alleviate thirst and dry mouth in critically ill patients: A randomised controlled trial.症状管理减轻危重症患者口渴和口干:一项随机对照试验。
Aust Crit Care. 2022 Mar;35(2):123-129. doi: 10.1016/j.aucc.2021.04.002. Epub 2021 Jun 10.
10
Could the use of saliva substitutes improve food oral processing in individuals with xerostomia? A systematic review.唾液替代品的使用能否改善口干个体的食物口腔加工?系统评价。
J Texture Stud. 2021 Jun;52(3):278-293. doi: 10.1111/jtxs.12591. Epub 2021 Mar 1.