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基于深度学习的髌骨关节高度自动测量系统:一项多中心回顾性研究。

Deep learning-based automatic measurement system for patellar height: a multicenter retrospective study.

机构信息

Department of Bone and Joint Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

College of Information and Communication Engineering, Harbin Engineering University, Heilongjiang, Harbin, China.

出版信息

J Orthop Surg Res. 2024 May 31;19(1):324. doi: 10.1186/s13018-024-04809-6.

Abstract

BACKGROUND

The patellar height index is important; however, the measurement procedures are time-consuming and prone to significant variability among and within observers. We developed a deep learning-based automatic measurement system for the patellar height and evaluated its performance and generalization ability to accurately measure the patellar height index.

METHODS

We developed a dataset containing 3,923 lateral knee X-ray images. Notably, all X-ray images were from three tertiary level A hospitals, and 2,341 cases were included in the analysis after screening. By manually labeling key points, the model was trained using the residual network (ResNet) and high-resolution network (HRNet) for human pose estimation architectures to measure the patellar height index. Various data enhancement techniques were used to enhance the robustness of the model. The root mean square error (RMSE), object keypoint similarity (OKS), and percentage of correct keypoint (PCK) metrics were used to evaluate the training results. In addition, we used the intraclass correlation coefficient (ICC) to assess the consistency between manual and automatic measurements.

RESULTS

The HRNet model performed excellently in keypoint detection tasks by comparing different deep learning models. Furthermore, the pose_hrnet_w48 model was particularly outstanding in the RMSE, OKS, and PCK metrics, and the Insall-Salvati index (ISI) automatically calculated by this model was also highly consistent with the manual measurements (intraclass correlation coefficient [ICC], 0.809-0.885). This evidence demonstrates the accuracy and generalizability of this deep learning system in practical applications.

CONCLUSION

We successfully developed a deep learning-based automatic measurement system for the patellar height. The system demonstrated accuracy comparable to that of experienced radiologists and a strong generalizability across different datasets. It provides an essential tool for assessing and treating knee diseases early and monitoring and rehabilitation after knee surgery. Due to the potential bias in the selection of datasets in this study, different datasets should be examined in the future to optimize the model so that it can be reliably applied in clinical practice.

TRIAL REGISTRATION

The study was registered at the Medical Research Registration and Filing Information System (medicalresearch.org.cn) MR-61-23-013065. Date of registration: May 04, 2023 (retrospectively registered).

摘要

背景

髌骨高度指数很重要;然而,测量程序既耗时,又容易在观察者之间和内部出现显著的变异性。我们开发了一种基于深度学习的髌骨高度自动测量系统,并评估了其性能和泛化能力,以准确测量髌骨高度指数。

方法

我们开发了一个包含 3923 个外侧膝关节 X 射线图像的数据集。值得注意的是,所有 X 射线图像均来自三家三级 A 医院,经过筛选后,有 2341 例病例纳入分析。通过手动标记关键点,使用残差网络(ResNet)和高分辨率网络(HRNet)进行人体姿态估计架构的模型来测量髌骨高度指数。使用各种数据增强技术来增强模型的鲁棒性。使用均方根误差(RMSE)、目标关键点相似度(OKS)和正确关键点百分比(PCK)来评估训练结果。此外,我们使用组内相关系数(ICC)来评估手动和自动测量之间的一致性。

结果

通过比较不同的深度学习模型,HRNet 模型在关键点检测任务中表现出色。此外,pose_hrnet_w48 模型在 RMSE、OKS 和 PCK 方面表现尤为出色,并且该模型自动计算的 Insall-Salvati 指数(ISI)也与手动测量高度一致(组内相关系数[ICC],0.809-0.885)。这一证据证明了该深度学习系统在实际应用中的准确性和泛化能力。

结论

我们成功开发了一种基于深度学习的髌骨高度自动测量系统。该系统的准确性可与有经验的放射科医生相媲美,并且在不同数据集之间具有很强的泛化能力。它为早期评估和治疗膝关节疾病以及膝关节手术后的监测和康复提供了重要工具。由于本研究中数据集选择存在潜在偏倚,未来应检查不同的数据集以优化模型,使其能够可靠地应用于临床实践。

试验注册

该研究在医学研究注册和备案信息系统(medicalresearch.org.cn)MR-61-23-013065 上注册。注册日期:2023 年 5 月 4 日(追溯注册)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e64/11141039/eb4c78e344ad/13018_2024_4809_Fig1_HTML.jpg

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