Witten/Herdecke University, Witten, Märkische Clinics Health Holding Ltd., Clinic Lüdenscheid, Department of Internal Medicine, Pulmonary Division, Internal Intensive Care Medicine, Infectiology, and Sleep Medicine, Germany.
Witten/Herdecke University, Witten, Märkische Clinics Health Holding Ltd., Clinic Lüdenscheid, Department of Internal Medicine, Pulmonary Division, Internal Intensive Care Medicine, Infectiology, and Sleep Medicine, Germany.
J Infect Public Health. 2024 Jul;17(7):102458. doi: 10.1016/j.jiph.2024.05.046. Epub 2024 May 27.
The COVID-19 pandemic has significantly impacted global health and prompted studies on its effects across various diseases. Recent data suggest a potential correlation between COVID-19 and a decrease in lung cancer incidence. This study examines the association between COVID-19 infection and changes in lung cancer cases.
We conducted a retrospective analysis of medical records from Clinic Lüdenscheid, Germany, from January 1, 2018, to December 31, 2021, comparing lung cancer cases before and during the pandemic. Demographic characteristics and cancer stages were also assessed.
We evaluated 523 patients; 269 pre-COVID and 254 during COVID. While the overall number of cases declined, a significant increase in advanced stage cancers was noted during COVID (P = 0.04). The adjusted incidence rates showed a nuanced decrease from approximately 33 cases per 100,000 pre-COVID to 31 during COVID.
This retrospective study suggests a modest decline in lung cancer incidence and an increase in advanced stages during COVID. Further comparisons with national data indicate a similar trend across Germany, with a decrease of about 3 % in lung cancer diagnoses post-2020, highlighting potential pandemic impacts on cancer detection.
COVID-19 大流行对全球健康产生了重大影响，并促使人们对其在各种疾病中的影响进行了研究。最近的数据表明，COVID-19 与肺癌发病率下降之间可能存在关联。本研究旨在探讨 COVID-19 感染与肺癌病例变化之间的关系。
我们对德国吕登沙伊德诊所 2018 年 1 月 1 日至 2021 年 12 月 31 日的病历进行了回顾性分析，比较了大流行前后的肺癌病例。还评估了人口统计学特征和癌症分期。
我们评估了 523 名患者；269 名 COVID-19 前，254 名 COVID-19 期间。虽然病例总数有所下降，但 COVID-19 期间晚期癌症的数量显著增加（P=0.04）。调整后的发病率显示，COVID-19 前约为每 100,000 人 33 例，COVID-19 期间降至 31 例，呈细微下降趋势。
本回顾性研究表明，COVID-19 期间肺癌发病率略有下降，晚期癌症分期增加。与全国数据的进一步比较表明，德国也呈现出类似的趋势，2020 年后肺癌诊断减少了约 3%，这突显了大流行对癌症检测的潜在影响。
