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伴有双侧视网膜中央动脉阻塞和舌坏死的巨细胞动脉炎

Giant Cell Arteritis With Bilateral Central Retinal Artery Occlusion and Tongue Necrosis.

作者信息

Brar Anand S, Nanda Ridham, Narayanan Raja, Padhy Srikanta K

机构信息

Ophthalmology, LV Prasad Eye Institute, Mithu Tulsi Chanrai (MTC) Campus, Bhubaneswar, IND.

Ophthalmology, All India Institute of Medical Sciences, Vijaypur, Jammu, Jammu, IND.

出版信息

Cureus. 2024 May 2;16(5):e59554. doi: 10.7759/cureus.59554. eCollection 2024 May.

Abstract

This case report describes a complicated case of giant cell arteritis (GCA) with tongue necrosis and bilateral central retinal artery occlusion (CRAO). An 81-year-old male patient with a history of recent retinal artery occlusion, ischemic stroke, and hypertensive emergency was evaluated. Clinical examination, including a visual acuity assessment, fundus evaluation, and oral examination, was performed. Laboratory investigations, such as erythrocyte sedimentation rate (ESR), were conducted. A temporal artery biopsy was performed to confirm the diagnosis of GCA. The patient presented with sudden vision loss in the left eye following a prior episode of retinal artery occlusion in the right eye. Ophthalmoscopic examination revealed CRAO in the left eye. Additionally, tongue necrosis, a rare manifestation of GCA, was observed. The ESR was significantly elevated. A temporal artery biopsy supported the diagnosis of GCA. The patient was promptly referred for immunologist consultation and initiated on intravenous methylprednisolone therapy. This case highlights the diverse and potentially devastating nature of GCA, involving ocular and systemic manifestations. Bilateral CRAO and tongue necrosis are rare but significant complications of GCA. Prompt diagnosis and early initiation of corticosteroid therapy are crucial to prevent irreversible visual loss and further complications. A multidisciplinary approach involving ophthalmologists and other specialists is essential for the comprehensive management of GCA.

摘要

本病例报告描述了一例伴有舌坏死和双侧视网膜中央动脉阻塞(CRAO)的复杂巨细胞动脉炎(GCA)病例。对一名81岁男性患者进行了评估,该患者有近期视网膜动脉阻塞、缺血性中风和高血压急症病史。进行了包括视力评估、眼底检查和口腔检查在内的临床检查。进行了红细胞沉降率(ESR)等实验室检查。进行了颞动脉活检以确诊GCA。该患者在右眼先前发生视网膜动脉阻塞后,左眼突然失明。眼底检查显示左眼有CRAO。此外,还观察到舌坏死,这是GCA的一种罕见表现。ESR显著升高。颞动脉活检支持GCA的诊断。该患者被迅速转诊至免疫科会诊,并开始接受静脉注射甲泼尼龙治疗。本病例突出了GCA多样且可能具有破坏性的性质,涉及眼部和全身表现。双侧CRAO和舌坏死是GCA罕见但严重的并发症。及时诊断并尽早开始使用皮质类固醇治疗对于预防不可逆的视力丧失和进一步并发症至关重要。涉及眼科医生和其他专家的多学科方法对于GCA的综合管理至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5a/11144274/60a9c6f9c990/cureus-0016-00000059554-i01.jpg

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