Nath Tilak Chandra, Tusher Proloy Chakraborty, Siddiki Tarek, Nyema Jannatul, Bhattacharjee Tiluttom, Dey Nilotpal, Mukutmoni Mandira, Islam Kazi Mehetazul, Bhuiyan Jamal Uddin
Department of Parasitology, Sylhet Agricultural University, Sylhet, Bangladesh.
Parasite Resource Bank, Sylhet, Bangladesh.
IJID Reg. 2024 May 8;11:100376. doi: 10.1016/j.ijregi.2024.100376. eCollection 2024 Jun.
The zoonotic hookworm species has drawn more attention recently because of its potential impact on public health. Although and are more common, is still known to play a major role in human infections, particularly in regions where close human-animal interactions are prevalent. While there has been a notable increase in documenting the presence of in the Asia-Pacific area, bottlenecks remains in understanding its epidemiology in Bangladesh. This report highlights the first documented case of infection isolated and identified in a 15-year-old girl experiencing frequent diarrhea and weakness, residing in an urban tea garden area in Sylhet, Bangladesh. Microscopic examination of stool samples revealed the presence of hookworm eggs and subsequent culture led to the observation of larvae. Molecular investigation by amplifying Internal Transcribed Spacer (ITS1+) regions of the ribosomal deoxyribonucleic acid (rDNA) confirmed the infection as . The identification of in a human host in Bangladesh carries significant implications for global health. The careful measurement of eggs and larvae, coupled with molecular analysis, serves as an appropriate diagnostic strategy for confirming the infections. This finding emphasizes the emergence of as a zoonotic infection in endemic regions and calls for increased awareness among healthcare professionals and the general public.
人兽共患钩虫物种最近因其对公共卫生的潜在影响而受到更多关注。虽然[此处原文缺失两种钩虫名称]更为常见，但[此处原文缺失特定钩虫名称]仍被认为在人类感染中起主要作用，特别是在人与动物密切互动普遍的地区。虽然亚太地区记录到[此处原文缺失特定钩虫名称]存在的情况显著增加，但在孟加拉国了解其流行病学仍存在瓶颈。本报告重点介绍了在孟加拉国锡尔赫特一个城市茶园地区一名15岁经常腹泻和虚弱的女孩身上首次记录到的[此处原文缺失特定钩虫名称]感染病例并进行了鉴定。粪便样本的显微镜检查发现了钩虫卵，随后的培养观察到了幼虫。通过扩增核糖体脱氧核糖核酸（rDNA）的内部转录间隔区（ITS1+）进行分子研究，确认感染为[此处原文缺失特定钩虫名称]。在孟加拉国人类宿主中鉴定出[此处原文缺失特定钩虫名称]对全球健康具有重大意义。对虫卵和幼虫的仔细测量以及分子分析，是确认感染的合适诊断策略。这一发现强调了[此处原文缺失特定钩虫名称]在流行地区作为一种人兽共患感染的出现，并呼吁提高医疗专业人员和公众的认识。
