Rosas Herrera Ana, Parker Ashley B, Chaskes Mark, Askin Frederic, Monk Aurelia S, Stephens John R, Thorp Brian D, Ebert Charles S, Senior Brent A, Kimple Adam J, Kong Keonho A
Department of Otolaryngology-Head and Neck Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
Clin Med Insights Case Rep. 2024 May 31;17:11795476241255563. doi: 10.1177/11795476241255563. eCollection 2024.
Infratemporal fossa (ITF) tumors are rare in children and may present with a variety of symptoms. Teratomas are neoplasms derived from the 3 germ layers and approximately 6% to 10% are within the head and neck. Our study discusses one of the first reported cases of teratoma in the ITF in a pediatric patient. A 3-year-old girl presents with 2 years of recurrent monthly left periorbital swelling accompanied by fevers, skin discoloration, and pain. Prior episodes were treated with antibiotics with incomplete resolution. Imaging revealed a cystic lesion centered in the ITF. She was taken for endoscopic endonasal biopsy of the lesion and had no complications. Pathology revealed a mature teratoma composed primarily of pancreatic tissue. Providers should consider masses such as teratoma in the differential for ITF tumors and periorbital edema unresponsive to typical treatment.
颞下窝（ITF）肿瘤在儿童中较为罕见，可能会出现多种症状。畸胎瘤是源自三个胚层的肿瘤，约6%至10%位于头颈部。我们的研究讨论了儿科患者中首例报道的颞下窝畸胎瘤病例之一。一名3岁女孩出现反复每月左侧眶周肿胀2年，伴有发热、皮肤变色和疼痛。先前发作时使用抗生素治疗，但未完全缓解。影像学检查显示以颞下窝为中心的囊性病变。她接受了该病变的鼻内镜下活检，未出现并发症。病理检查显示为主要由胰腺组织构成的成熟畸胎瘤。医疗人员在鉴别诊断颞下窝肿瘤和对常规治疗无反应的眶周水肿时，应考虑畸胎瘤等肿块。
