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一名老年女性的抗中性粒细胞胞浆抗体相关性系统性血管炎最初表现为周围神经病变

ANCA-associated systemic vasculitis initially mimicking peripheral neuropathy in an elderly woman.

作者信息

He Xiaojie, Wang Yaqing, Li Xiaodong

机构信息

Xiaojie He, Graduate School of Hebei Medical University, Shijiazhuang 050017, Hebei, China.

Yaqing Wang, Graduate School of Chengde Medical University, Chengde, 06700, Hebei, China.

出版信息

Pak J Med Sci. 2024 May-Jun;40(5):1042-1045. doi: 10.12669/pjms.40.5.9070.

Abstract

Anti-neutrophil cytoplasmic antibodies (ANCA)-associated systemic vasculitis (AASV) is a rare systemic immunological condition that predominantly impacts small arteries, veins, and capillaries, often leading to kidney damage and pulmonary injury. It is important to note that individuals primarily presenting with peripheral neuropathy (PN) are uncommon in AASV, which can result in significant misdiagnosis or undiagnosed cases. The severity and location of PN can vary among patients. In this article, we present a case of an AASV patient initially showing signs of PN. This case highlights the significance of considering AASV as a potential cause of unexplained neurological symptoms. Timely identification and proper treatment are essential for improving the survival rate and functional prognosis of AASV patients.

摘要

抗中性粒细胞胞浆抗体(ANCA)相关性系统性血管炎(AASV)是一种罕见的系统性免疫疾病,主要影响小动脉、静脉和毛细血管,常导致肾脏损害和肺部损伤。需要注意的是,以周围神经病变(PN)为主诉的个体在AASV中并不常见,这可能导致严重的误诊或漏诊情况。PN的严重程度和部位在患者之间可能有所不同。在本文中,我们报告了一例最初表现为PN症状的AASV患者。该病例强调了将AASV视为不明原因神经症状潜在病因的重要性。及时识别和恰当治疗对于提高AASV患者的生存率和功能预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bace/11140351/e560b69b765a/PJMS-40-1042-g001.jpg

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