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用于使用放射变色胶片校准P眼施源器的相对剂量测定系统的开发。

Development of a Relative Dosimetric System for Calibration of P Eye Applicators Using Radiochromic Films.

作者信息

Nazempoor Alireza, Poorbaygi Hosein, Aghamiri Seyed Mahmud Reza, Javanshir Mohammad Reza, Sheibani Shahab, Naghdi Reza, Moradi Somayeh, Habibpanah Ali

机构信息

Departments of Medical Radiation Engineering, Shahid Beheshti University, Tehran, Iran.

Radiation Application Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.

出版信息

J Med Phys. 2024 Jan-Mar;49(1):49-55. doi: 10.4103/jmp.jmp_99_23. Epub 2024 Mar 30.

DOI:10.4103/jmp.jmp_99_23
PMID:38828074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11141744/
Abstract

INTRODUCTION

Beta irradiation after bare scleral surgery of primary pterygium is an effective and safe treatment, which reduces the risk of local recurrence.

PURPOSE

Obtaining the reference dose rate for a radioactive applicator consisting of a plate as a 32P absorber, a steel window and a steel capsule.

METHODS

Relative dosimetry and dose profile were measured using two types of radiochromic films, HD-810 and EBT1, for the P applicator and were compared with Monte Carlo simulation data. Dose uniformity in the P applicator was obtained with radiochromic HD-810 film.

RESULTS

The measurement depth dose distribution data at distances up to 3.8 mm were compared with calculation data, and the values were not found to differ statistically. Depth dose distribution with a large dose gradient was determined and the dose rate data obtained 0.0053 ± 9.9% in unit of Gy/s.mCi at a 0.1 mm depth distance. Practical results indicated that the dose nonuniformity and the maximum symmetrical for the P applicator were 11.5% and 9.2%, respectively.

CONCLUSIONS

Our experiments show that the use of the radiochromic film to perform the relative dosimetric checks is feasible and the activity value with acceptable error can be determined through this indirect method.

摘要

引言

原发性翼状胬肉巩膜裸露术后进行β射线照射是一种有效且安全的治疗方法，可降低局部复发风险。

目的

获取一种由作为³²P吸收体的平板、钢窗和钢胶囊组成的放射性敷贴器的参考剂量率。

方法

使用HD - 810和EBT1两种类型的放射变色膜对³²P敷贴器进行相对剂量测定和剂量分布测量，并与蒙特卡罗模拟数据进行比较。使用放射变色HD - 810膜获得³²P敷贴器中的剂量均匀性。

结果

将高达3.8毫米距离处的测量深度剂量分布数据与计算数据进行比较，未发现数值有统计学差异。确定了具有大剂量梯度的深度剂量分布，在0.1毫米深度距离处获得的剂量率数据为0.0053±9.9%（单位为Gy/s.mCi）。实际结果表明，³²P敷贴器的剂量不均匀性和最大对称性分别为11.5%和9.2%。

结论

我们的实验表明，使用放射变色膜进行相对剂量测定检查是可行的，并且可以通过这种间接方法确定具有可接受误差的活度值。

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本文引用的文献

1
Dosimetry of a new P-32 ophthalmic applicator.一种新型 P-32 眼用施源器的剂量学研究。
Med Phys. 2011 Nov;38(11):6143-51. doi: 10.1118/1.3644843.
2
Ophthalmic applicators: an overview of calibrations following the change to SI units.眼科涂抹器：向国际单位制转换后的校准概述。
Med Phys. 2009 May;36(5):1473-7. doi: 10.1118/1.3098943.
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Potential use of P-32 ophthalmic applicator: Monte Carlo simulations for design and dosimetry.P-32眼科敷贴器的潜在用途：用于设计和剂量测定的蒙特卡罗模拟
Med Phys. 2008 May;35(5):1854-8. doi: 10.1118/1.2896076.
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Recommendations on detectors and quality control procedures for brachytherapy beta sources.近距离放射治疗β射线源的探测器及质量控制程序建议。
Radiother Oncol. 2006 Feb;78(2):223-9. doi: 10.1016/j.radonc.2005.12.006. Epub 2006 Feb 2.
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Prevention of pterygium recurrence by postoperative single-dose beta-irradiation: a prospective randomized clinical double-blind trial.术后单次剂量β射线照射预防翼状胬肉复发：一项前瞻性随机临床双盲试验
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Postoperative beta radiation treatment of pterygium.翼状胬肉术后β射线放射治疗
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