Yu Rongbo, Xiang Yiliu, Dou Haoduan, Li Hewen, Zheng Yuyang, Chen Bin
Department of Minimally Invasive Spine Surgery, Chengde Medical University Affiliated Hospital, Chengde, Hebei, 067000, People's Republic of China.
J Pain Res. 2024 May 28;17:1953-1965. doi: 10.2147/JPR.S454771. eCollection 2024.
Endoscopic surgery is a minimally invasive option for effectively addressing lumbar degenerative diseases. This study aimed to describe the specific technology of percutaneous transforaminal endoscopic lumbar foraminotomy (PTELF) as a therapeutic intervention for managing radicular leg pain (RLP) resulting from stable degenerative lumbar isthmic spondylolisthesis (DLIS) and to present the associated clinical results.
From March 2022 and April 2023, 25 patients were diagnosed with single-level stable DLIS with RLP and underwent PTELF. Clinical assessments utilized the visual analog scale (VAS), Oswestry Disability Index (ODI), and modified MacNab criteria. All endoscopic surgery videos were reviewed to interpret the pathology associated with DLIS.
The mean age of the cohort was 65.3 ± 11.0 years. The mean preoperative ODI score, VAS score for low back, and VAS score of the leg were 64.1 ± 8.2, 7.0 ± 0.7, and 7.3 ± 0.8, respectively. These scores significantly improved to 16.3 ± 10.4, 2.0 ± 0.6, and 1.7 ± 1.0 at the final follow-up, respectively (P<0.01). The modified MacNab criteria indicated "good" or "excellent" outcomes in 92.0% of cases. Analysis of 23 surgical videos revealed 15 patients with disc herniation, nine with lower vertebral endplate involvement, consistent presence of uneven bone spurs (at the proximal lamina stump and around the foramen), and accumulated scars. Two patients experienced postoperative dysesthesia, and one encountered a recurrence of RLP.
PTELF emerges as a potentially safe and effective procedure for alleviating RLP in patients with stable DLIS. However, additional evidence and extended follow-up periods are imperative to evaluate the feasibility and potential risks associated with PTELF.
内镜手术是有效治疗腰椎退行性疾病的一种微创选择。本研究旨在描述经皮椎间孔内镜下腰椎椎间孔切开术(PTELF)作为治疗因稳定型退行性腰椎峡部裂(DLIS)导致的放射性腿痛(RLP)的一种治疗干预措施的具体技术,并呈现相关临床结果。
2022年3月至2023年4月,25例被诊断为单节段稳定型DLIS伴RLP的患者接受了PTELF。临床评估采用视觉模拟量表(VAS)、Oswestry功能障碍指数(ODI)和改良MacNab标准。对所有内镜手术视频进行回顾,以解读与DLIS相关的病理情况。
该队列患者的平均年龄为65.3±11.0岁。术前平均ODI评分、腰痛VAS评分和腿痛VAS评分分别为64.1±8.2、7.0±0.7和7.3±0.8。在末次随访时,这些评分分别显著改善至16.3±10.4、2.0±0.6和1.7±1.0(P<0.01)。改良MacNab标准显示92.0%的病例结果为“良好”或“优秀”。对23个手术视频的分析显示,15例患者存在椎间盘突出,9例患者有下位椎体终板受累,持续存在不均匀骨赘(在近端椎板残端和椎间孔周围)以及瘢痕形成。2例患者术后出现感觉异常,1例患者出现RLP复发。
PTELF似乎是缓解稳定型DLIS患者RLP的一种潜在安全有效的手术方法。然而,需要更多证据和更长的随访期来评估PTELF的可行性和潜在风险。