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药物洗脱球囊治疗冠状动脉搭桥术后即刻ST段抬高型心肌梗死:一例病例报告

Drug-eluting balloon to treat immediate post-coronary artery bypass grafting ST-elevation myocardial infarction: a case report.

作者信息

Shah Muhammad Usman, Haider Muhammad Anis, Poudyal Krishna, Loubani Mahmoud, Naqvi Syed Yaseen

机构信息

Joseph Banks Laboratories, University of Lincoln, Beevor St, Lincoln LN6 7DL, UK.

Department of Cardiology and Cardiac Surgery, Hull University Teaching Hospitals, Cottingham, UK.

出版信息

Eur Heart J Case Rep. 2024 May 15;8(6):ytae245. doi: 10.1093/ehjcr/ytae245. eCollection 2024 Jun.

Abstract

BACKGROUND

Coronary artery bypass graft (CABG) surgery represents a major cardiovascular operation and may be associated with post-operative ST-elevation myocardial infarction (STEMI) due to graft failure. This is challenging to diagnose and treat as the implanted grafts may be prone to complications when treated percutaneously with drug-eluting stents.

CASE SUMMARY

A man in his 60 s underwent CABG and developed new persistent ST elevations of 2 mm in anterior leads with no significant chest pain, although, administered with intravenous opiates post-operatively. Transthoracic echocardiography was non-diagnostic. Invasive angiography performed emergently showed a thrombotic occlusion of the mid-left anterior descending artery at the site of the anastomosis with the left internal mammary artery (LIMA) graft. Intervention via the graft was considered high risk of complications, therefore, native coronary arteries were used to approach the occlusion, which was successfully cleared with a combination balloon angioplasty with a semi-compliant and then a drug-eluting balloon. The LIMA started working again with the resolution of ST elevation and no immediate complications.

DISCUSSION

Early post-operative ST elevations in continuous leads should not be ignored as they often may be the only feature of new-onset STEMI. Drug-eluting balloons represent a feasible and possibly safer option than drug-eluting stents to treat these conditions.

摘要

背景

冠状动脉旁路移植术(CABG)是一项重大的心血管手术,术后可能因移植血管失败而并发ST段抬高型心肌梗死(STEMI)。由于经皮使用药物洗脱支架治疗时植入的移植血管可能易于出现并发症,因此该病的诊断和治疗具有挑战性。

病例摘要

一名60多岁男性接受了冠状动脉旁路移植术,术后前壁导联出现新的持续2毫米ST段抬高,虽术后静脉注射了阿片类药物,但无明显胸痛。经胸超声心动图检查未明确诊断。紧急进行的有创血管造影显示,左前降支中段在与左乳内动脉(LIMA)移植血管吻合处出现血栓性闭塞。经移植血管进行干预被认为并发症风险高,因此,通过自身冠状动脉处理闭塞病变,先用半顺应性球囊血管成形术,然后用药物洗脱球囊成功清除了血栓。随着ST段抬高消失,左乳内动脉恢复功能,且无即刻并发症。

讨论

持续导联术后早期ST段抬高不应被忽视,因为它们往往可能是新发STEMI的唯一表现。与药物洗脱支架相比,药物洗脱球囊是治疗这些病症的一种可行且可能更安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1414/11144022/06501a830a6b/ytae245il2.jpg

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