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罗哌卡因蛛网膜下腔阻滞对近期蝎子蜇伤患者的疗效：病例系列研究。

Efficacy of Ropivacaine for Sub-Arachnoid Block in Patients with Recent History of Scorpion Sting: A case series.

机构信息

Department of Anaesthesia & Critical Care, Chirayu Medical College & Hospital, Bhopal, India.

出版信息

Sultan Qaboos Univ Med J. 2024 May;24(2):272-275. doi: 10.18295/squmj.7.2023.046. Epub 2024 May 27.

DOI:10.18295/squmj.7.2023.046
PMID:38828244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11139357/
Abstract

Failure of sub-arachnoid block (SAB), due to resistance to bupivacaine after a recent scorpion sting can lead to multiple block attempts and subsequent conversion to general anaesthesia. We report this case series of 10 patients with successful SAB with newly launched 0.75% hyperbaric ropivacaine, in patients with recent scorpion sting. Thus, intrathecal hyperbaric ropivacaine may be considered as the local anaesthetic agent of choice in patients with scorpion sting to prevent failure of SAB.

摘要

由于近期蝎子蜇伤后对布比卡因产生耐药性，导致蛛网膜下隙阻滞（SAB）失败，可能需要多次阻滞尝试，并随后转为全身麻醉。我们报告了 10 例近期蝎子蜇伤患者成功行 SAB 的病例系列研究，使用的是新推出的 0.75%重比重罗哌卡因。因此，对于近期蝎子蜇伤的患者，椎管内应用重比重罗哌卡因可作为预防 SAB 失败的首选局麻药。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec13/11139357/c66a4e4b5c33/squmj2405-272-275f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec13/11139357/0616879844dd/squmj2405-272-275f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec13/11139357/c66a4e4b5c33/squmj2405-272-275f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec13/11139357/0616879844dd/squmj2405-272-275f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec13/11139357/c66a4e4b5c33/squmj2405-272-275f2.jpg

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本文引用的文献

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Scorpion bite and failed spinal anesthesia: is ropivacaine the answer?蝎子蜇伤与脊髓麻醉失败：罗哌卡因是答案吗？
Minerva Anestesiol. 2023 Apr;89(4):368-369. doi: 10.23736/S0375-9393.22.16958-0.
2
Bromage motor blockade score - a score that has lasted more than a lifetime.布罗玛奇运动阻滞评分——一个持续时间超过一生的评分。
Can J Anaesth. 2018 Jul;65(7):837-838. doi: 10.1007/s12630-018-1101-7. Epub 2018 Mar 5.
3
Scorpion bite, a sting to the heart!蝎子蜇伤，刺痛心脏！
Indian J Crit Care Med. 2015 Apr;19(4):233-6. doi: 10.4103/0972-5229.154570.
4
Scorpion envenomation.蝎子蜇伤。
N Engl J Med. 2014 Jul 31;371(5):457-63. doi: 10.1056/NEJMra1401108.
5
Different effects of local anesthetics on extracellular signal-regulated kinase phosphorylation in rat dorsal horn neurons.局部麻醉剂对大鼠背角神经元细胞外信号调节激酶磷酸化的不同影响。
Eur J Pharmacol. 2014 Jul 5;734:132-6. doi: 10.1016/j.ejphar.2014.03.048. Epub 2014 Apr 12.
6
Effect of previous scorpion bite(s) on the action of intrathecal bupivacaine: A case control study.既往蝎子蜇伤对鞘内布比卡因作用的影响：一项病例对照研究。
Indian J Anaesth. 2013 May;57(3):236-40. doi: 10.4103/0019-5049.115593.
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[Effects of ropivacaine on GABA-activated currents in isolated dorsal root ganglion neurons in rats].[罗哌卡因对大鼠离体背根神经节神经元中γ-氨基丁酸激活电流的影响]
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