Natarajan Ezhilarasan, Augustin Felix
Department of Mathematics, School of Advanced Sciences, Vellore Institute of Technology, Chennai, India.
Heliyon. 2024 May 21;10(11):e31416. doi: 10.1016/j.heliyon.2024.e31416. eCollection 2024 Jun 15.
Tuberculosis (TB) diagnosis poses a formidable challenge in global healthcare, particularly impacting older individuals and pregnant women. Diagnosing TB disease during pregnancy and in comorbid patients is more challenging due to overlapping symptoms with normal pregnancy conditions and existing treatments for other diseases, necessitating careful assessment to differentiate TB symptoms from those of other underlying conditions. To address this issue, this study designs a novel bipolar fuzzy decision-support system by integrating the concept of complex proportional assessment (COPRAS) and a technique for order preference by similarity to the ideal solution (TOPSIS) approaches using bipolar heptagonal fuzzy numbers. The approach is utilized to assess the high-risk of TB coinfection disease in pregnant women. The bipolar fuzzy set provides positive and negative membership degrees of an element, which divulge a balanced perspective by both the presence and absence of the disease. Additionally, a defuzzification algorithm is proposed for bipolar heptagonal fuzzy numbers, converting bipolar heptagonal fuzzy into a bipolar crisp score (CBHpFBCS). The bipolar fuzzy entropy measure is utilized to weight the criteria. The findings highlight that TB+HIV coinfection is more severe in pregnant women compared to other TB comorbidities. Finally, sensitivity and comparative analyses are executed across diverse criteria weight scenarios and with existing fuzzy multi-criteria decision-making (MCDM) methods to validate the robustness of the proposed method and its outcomes.
结核病(TB)诊断在全球医疗保健领域构成了一项艰巨挑战,尤其对老年人和孕妇产生影响。由于妊娠正常情况和其他疾病现有治疗方法的症状重叠,在孕期和合并症患者中诊断结核病更为困难,因此需要仔细评估以区分结核病症状与其他潜在病症的症状。为解决这一问题,本研究通过整合复杂比例评估(COPRAS)概念以及使用双极七边形模糊数的理想解相似排序法(TOPSIS)方法,设计了一种新型双极模糊决策支持系统。该方法用于评估孕妇结核病合并感染疾病的高风险。双极模糊集提供元素的正隶属度和负隶属度,通过疾病的存在和不存在揭示平衡的观点。此外,针对双极七边形模糊数提出了一种去模糊化算法,将双极七边形模糊转换为双极清晰分数(CBHpFBCS)。利用双极模糊熵测度对标准进行加权。研究结果突出表明,与其他结核病合并症相比,孕妇中的结核病合并人类免疫缺陷病毒(HIV)感染更为严重。最后,在不同标准权重情景下并与现有的模糊多准则决策(MCDM)方法进行敏感性和比较分析,以验证所提出方法及其结果的稳健性。