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顶体蛋白酶对透明带进行有限且特定的蛋白水解作用。

Limited and specific proteolysis of the zona pellucida by acrosin.

作者信息

Urch U A, Wardrip N J, Hedrick J L

出版信息

J Exp Zool. 1985 Mar;233(3):479-83. doi: 10.1002/jez.1402330317.

DOI:10.1002/jez.1402330317
PMID:3882882
Abstract

The proteolytic action of boar sperm acrosin on its natural substrate, the zona pellucida, was investigated. Acrosin exhibited substrate specificity for the zona pellucida and differentially hydrolyzed the glycoprotein families composing the zona pellucida. In contrast to acrosin, trypsin was a less-specific protease in terms of zona pellucida hydrolysis.

摘要

研究了公猪精子顶体蛋白酶对其天然底物透明带的蛋白水解作用。顶体蛋白酶对透明带表现出底物特异性，并能差异性地水解构成透明带的糖蛋白家族。与顶体蛋白酶相比，就透明带水解而言，胰蛋白酶是一种特异性较低的蛋白酶。

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1
Limited and specific proteolysis of the zona pellucida by acrosin.顶体蛋白酶对透明带进行有限且特定的蛋白水解作用。
J Exp Zool. 1985 Mar;233(3):479-83. doi: 10.1002/jez.1402330317.
2
Proteolysis of the zona pellucida by acrosin: the nature of the hydrolysis products.
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Proteolysis of specific porcine zona pellucida glycoproteins by boar acrosin.
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Limited proteolysis of the porcine zona pellucida by homologous sperm acrosin.
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Identification of a zona-binding protein from boar spermatozoa as proacrosin.
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On the interaction of bull and boar acrosins with the zona pellucida of different mammalian species in vitro.公牛和公猪顶体蛋白酶与不同哺乳动物物种透明带的体外相互作用
Andrologia. 1985 Sep-Oct;17(5):417-25. doi: 10.1111/j.1439-0272.1985.tb01032.x.
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The interaction of boar sperm proacrosin with its natural substrate, the zona pellucida, and with polysulfated polysaccharides.公猪精子前顶体蛋白酶与其天然底物透明带以及多硫酸化多糖之间的相互作用。
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Zona pellucida-binding of boar sperm acrosin is associated with the N-terminal peptide of the acrosin B-chain (heavy chain).
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Binding of sperm proacrosin/beta-acrosin to zona pellucida glycoproteins is sulfate and stereodependent. Synthesis of a novel fertilization inhibitor.精子前顶体蛋白酶/β-顶体蛋白酶与透明带糖蛋白的结合是硫酸化和立体依赖性的。一种新型受精抑制剂的合成。
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Extraction, purification, biological effects and applications of acrosin: a review.顶体蛋白酶的提取、纯化、生物学效应及应用：综述
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Occurrence of reducing terminal N-acetylglucosamine 3-sulfate and fucosylated outer chains in acidic N-glycans of porcine zona pellucida glycoproteins.
猪透明带糖蛋白酸性N-聚糖中还原性末端N-乙酰葡糖胺3-硫酸盐和岩藻糖基化外链的出现情况。
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[Molecular biology of gamete conjugation].[配子结合的分子生物学]
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Caprine acrosin. Purification, characterization and proteolysis of the porcine zona pellucida.山羊顶体蛋白酶。猪透明带的纯化、特性鉴定及蛋白水解作用
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Determination of active, non-zymogen acrosin, proacrosin and total acrosin in different andrological patients.不同男科患者中活性非酶原顶体蛋白酶、酶原顶体蛋白酶和总顶体蛋白酶的测定。
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