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使用酯化小麦多孔淀粉和乳清分离蛋白对大蒜油进行微胶囊化:理化性质及体外消化过程中的释放行为。

Micro-encapsulation of garlic oil using esterified-wheat porous starch and whey protein isolate: Physicochemical properties, release behavior during in vitro digestion.

机构信息

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China; Shenzhen Boton Flavors and Fragrances Co., Ltd, Shenzhen, Guangdong 518000, China.

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou, Fujian, China.

出版信息

Int J Biol Macromol. 2024 Jun;272(Pt 1):132843. doi: 10.1016/j.ijbiomac.2024.132843. Epub 2024 Jun 1.

DOI:10.1016/j.ijbiomac.2024.132843
PMID:38830489
Abstract

The study aimed to inhibit the stimulating impact of garlic oil (GO) on the stomach and attain high release in the intestine during digestion. So, wheat porous starch (WPS) was modified with octenyl succinic acid (OSA) and malic acid (MA) to obtain esterified WPS, OWPS and MWPS, respectively. The differences in physicochemical, encapsulation, and digestive properties of two GO microcapsules, WPI/OWPS/GO and WPI/MWPS/GO microcapsules produced by using OWPS and MWPS as variant carrier materials and whey protein isolate (WPI) as the same coating agent, were compared. The results found that OWPS had greater amphiphilicity, while MWPS had better hydrophobicity and anti-digestive ability than WPS. Encapsulation efficiency of WPI/OWPS/GO (94.67 %) was significantly greater than WPI/MWPS/GO (91.44 %). The digestion inhibition and low GO release (approximately 23 %) of WPI/OWPS/GO and WPI/MWPS/GO microcapsules in the gastric phase resulted from the protective effect of WPI combined with the good adsorption and lipophilicity of OWPS and MWPS. Especially, WPI/OWPS/GO microcapsule was relatively stable in the gastric phase and had sufficient GO release (67.24 %) in the intestinal phase, which was significantly higher than WPI/MWPS/GO microcapsule (56.03 %), benefiting from the adsorption and digestive properties of OWPS, and resulting in a total cumulative GO release rate of 90.86 %.

摘要

本研究旨在抑制大蒜油(GO)对胃的刺激作用,并在消化过程中使其在肠道中实现高释放。因此,采用辛烯基琥珀酸(OSA)和苹果酸(MA)对小麦多孔淀粉(WPS)进行修饰,分别得到酯化 WPS、OWPS 和 MWPS。分别使用 OWPS 和 MWPS 作为变体载体材料和乳清蛋白分离物(WPI)作为相同的包衣剂来制备两种 GO 微胶囊,WPI/OWPS/GO 和 WPI/MWPS/GO 微胶囊,比较了它们在物理化学、包封和消化性质方面的差异。结果发现,OWPS 具有更大的两亲性,而 MWPS 比 WPS 具有更好的疏水性和抗消化能力。WPI/OWPS/GO(94.67%)的包封效率显著大于 WPI/MWPS/GO(91.44%)。WPI/OWPS/GO 和 WPI/MWPS/GO 微胶囊在胃相的消化抑制和低 GO 释放(约 23%)是由于 WPI 与 OWPS 和 MWPS 的良好吸附和疏水性结合的保护作用所致。特别是,WPI/OWPS/GO 微胶囊在胃相相对稳定,在肠相有足够的 GO 释放(67.24%),明显高于 WPI/MWPS/GO 微胶囊(56.03%),这得益于 OWPS 的吸附和消化特性,导致总累积 GO 释放率达到 90.86%。

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