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中耳植入物的外科病理学

Surgical pathology of middle ear implants.

作者信息

Schuknecht H F, Shi S R

出版信息

Laryngoscope. 1985 Mar;95(3):249-58.

PMID:3883089
Abstract

During the past 15 years a series of 25 middle ear implants was removed at the time of revision surgery and prepared for histological study. These revision operations were performed because of failure to control the disease and/or persistent or recurring hearing loss. The ossicular and cortical bone autografts showed similar behavior in that they underwent creeping substitution with vitalized bone in amounts varying from 0% to 83%. There was no correlation to duration of implantation. The four cartilage grafts, on macroscopic evaluation, showed a loss of rigidity. Two of three cartilage autografts showed a high rate of survival of chondrocytes. The two TORP prostheses showed extensive invasion of their porous spaces with foreign body giant cells. One of the latter, implanted for over four years showed fibrous replacement of plastic material. The two polyethylene tubes showed intraluminal foreign body reaction and new bone formation.

摘要

在过去15年里,一系列25个中耳植入物在翻修手术时被取出,并准备进行组织学研究。进行这些翻修手术是因为未能控制疾病和/或持续或反复出现听力损失。听骨和皮质骨自体移植物表现出相似的行为,即它们经历了由活性骨进行的爬行替代,替代量从0%到83%不等。这与植入持续时间无关。在宏观评估中,四个软骨移植物显示出硬度丧失。三个软骨自体移植物中的两个显示软骨细胞的高存活率。两个全听骨赝复物(TORP)显示其多孔空间被异物巨细胞广泛侵入。其中一个植入超过四年的移植物显示塑料材料被纤维组织替代。两个聚乙烯管显示管腔内有异物反应和新骨形成。

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