Krummel F J, Reck R, Meyer A
Univ.-HNO-Klinik Mainz.
Laryngol Rhinol Otol (Stuttg). 1987 Aug;66(8):409-11.
28 tympanoplastic procedures with destruction and reconstruction of the ossicular chain were performed in rabbits. Vitreous carbon implants were used as prosthetic material. The animals were followed up from 14 days to one year. In 23 cases extensive inflammation of the middle ear mucosa was observed macroscopically. The histological findings were formation of an increasing fibrous capsule with duration of time, permanent foreign body reaction at the surface of the implants and missing formation of new bone or contact with bone respectively. Thus vitreous carbon seems to be a less promising material in middle ear surgery.
对家兔进行了28例伴有听骨链破坏与重建的鼓室成形术。使用玻璃碳植入物作为修复材料。对动物进行了14天至1年的随访。在23例中,肉眼观察到中耳黏膜广泛炎症。组织学结果显示,随着时间推移,纤维囊逐渐形成,植入物表面出现永久性异物反应,且分别未形成新骨或与骨接触。因此,玻璃碳在中耳手术中似乎是一种前景不太乐观的材料。