某些二环、三环和四环芳烃单氯衍生物的沙门氏菌/微粒体诱变性
Salmonella/microsome mutagenicity of monochloro derivatives of some di-, tri- and tetracyclic aromatic hydrocarbons.
作者信息
Löfroth G, Nilsson L, Agurell E, Sugiyama T
出版信息
Mutat Res. 1985 Mar;155(3):91-4. doi: 10.1016/0165-1218(85)90123-5.
PMID:3883156
Abstract
A series of 8 monochloroarenes have been tested for mutagenicity in the Salmonella/microsome assay. None of the compounds was detectably active in the absence of mammalian activation whereas, depending on structure, some of the compounds were mutagenic in its presence having responses higher than those reported for the parent compounds.
摘要
已对一系列8种一氯芳烃进行了沙门氏菌/微粒体试验中的致突变性测试。在没有哺乳动物活化的情况下，这些化合物均未表现出可检测到的活性，而根据结构不同，其中一些化合物在有哺乳动物活化存在时具有致突变性，其反应高于母体化合物的报道。
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