Lawal Lukman, Buhari Ahmad Oyindamola, Jaji Tawakalitu Abdulateef, Alatare Abdulrahman Salaudeen, Adeyemo Abdulmalik Opeyemi, Olumoh Aishat Oluwakemi, Yusuff Yusuff Adesoji, Osborn Gabriel, Mogaji Abdulazeez Biodun, Adoto Bello Hussein, Ibrahim Nafisa Gbemisola, Saliu Waliyullahi Oluwafemi, Abdul-Rahman Toufik
Centre for Malaria and Other Tropical Diseases Ilorin Nigeria.
Faculty of Clinical Sciences University of Ilorin Ilorin Nigeria.
Health Sci Rep. 2024 Jun 2;7(6):e2122. doi: 10.1002/hsr2.2122. eCollection 2024 Jun.
Between 2000 and 2015, significant gains were recorded in reducing the global burden of malaria due to enhanced global collaboration and increased funding. However, progress has stagnated post-2015, and the COVID-19 pandemic seems to have reversed some of these gains, necessitating a critical reevaluation of interventions. This paper aims to analyze the setbacks and offer recommendations for advancement in malaria control and prevention in sub-Saharan Africa.
We conducted searches on Google Scholar, PubMed, and relevant organization websites to identify relevant studies on malaria control and prevention and associated challenges in sub-Saharan Africa from 2015 to the present. Additionally, studies on individual sub-Saharan African countries were reviewed to ensure comprehensiveness. Data from selected studies were extracted and analyzed using a narrative synthesis approach to offer a concise overview of the evidence.
We observe that the halt in progress of malaria control in sub-Saharan Africa has deep roots in socioeconomic, political, and environmental factors. These challenges are exacerbated by the population explosion in the region, low coverage of interventions due to funding deficits and incessant crises, and the degradation of the efficacy of existing malaria commodities.
Sub-Saharan Africa is at a crossroads in its fight against malaria. Promising new frontiers such as malaria vaccines, preventive monoclonal antibodies, new-generation insecticide-treated nets, and potentially artificial intelligence-driven technologies offer hope in advancing malaria control and prevention in the region. Through commitment and collaboration, leveraging these opportunities can help surmount challenges and ultimately eliminate malaria in sub-Saharan Africa.
2000年至2015年间,由于全球合作的加强和资金投入的增加,在减轻全球疟疾负担方面取得了显著进展。然而,2015年之后进展停滞,新冠疫情似乎逆转了其中一些成果,因此有必要对干预措施进行批判性重新评估。本文旨在分析挫折,并为撒哈拉以南非洲地区疟疾控制和预防工作的推进提供建议。
我们在谷歌学术、PubMed和相关组织网站上进行搜索,以识别2015年至今关于撒哈拉以南非洲地区疟疾控制和预防以及相关挑战的相关研究。此外,还审查了关于撒哈拉以南非洲各个国家的研究,以确保全面性。使用叙述性综合方法提取和分析所选研究的数据,以简要概述证据。
我们观察到,撒哈拉以南非洲地区疟疾控制进展的停滞在社会经济、政治和环境因素方面有着深刻根源。该地区的人口爆炸、由于资金短缺和持续危机导致的干预措施覆盖率低,以及现有疟疾防治用品效力的下降,都加剧了这些挑战。
撒哈拉以南非洲地区在抗击疟疾方面正处于十字路口。疟疾疫苗、预防性单克隆抗体、新一代经杀虫剂处理的蚊帐以及潜在的人工智能驱动技术等有前景的新领域,为推进该地区的疟疾控制和预防工作带来了希望。通过承诺和合作,利用这些机会有助于克服挑战,并最终在撒哈拉以南非洲消除疟疾。