"Aldo Ravelli" Center for Neurotechnology and Experimental Brain Therapeutics, Department of Health Sciences, University of Milan, Via Antonio di Rudinì 8, 20142, Milan, Italy.
Clinical Neurology Unit, Department of Health Sciences, Azienda Socio-Sanitaria Territoriale Santi Paolo E Carlo, University of Milan, Via Antonio di Rudinì 8, 20142, Milan, Italy.
Neurol Sci. 2024 Oct;45(10):4669-4677. doi: 10.1007/s10072-024-07626-1. Epub 2024 Jun 4.
The objective of this study was to encompass current knowledge about pathophysiological mechanisms of those specific hand postures or deformities caused by central nervous system disorders. In the era of high-resolution neuroimaging and molecular biology, clinicians are progressively losing confidence with neurological examination. Careful hand observation is of key importance in order to differentiate neurological from non-neurological conditions, central from peripheral aetiologies, and organic from functional disorders. Localizing the potential anatomical site is essential to properly conduct subsequent exams. We provided a practical guide for clinicians to recognize hand patterns caused by central nervous system disorders, avoiding mimicking conditions, thus optimizing and prompting the diagnostic pathway.
本研究的目的是涵盖中枢神经系统疾病引起的特定手部姿势或畸形的病理生理机制的现有知识。在高分辨率神经影像学和分子生物学时代，临床医生对神经系统检查的信心逐渐下降。仔细观察手部非常重要，以便将神经源性与非神经源性、中枢性与周围性病因以及器质性与功能性障碍区分开来。确定潜在的解剖部位对于正确进行后续检查至关重要。我们为临床医生提供了一种实用指南，以识别中枢神经系统疾病引起的手部模式，避免模仿病症，从而优化和推动诊断途径。
