Nebel Dennis, Thorwächter Christoph, Schröder Stefan, Wendler Toni
Labor für Biomechanik und Biomaterialien, Orthopädische Klinik - DIAKOVERE Annastift, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30625, Hannover, Deutschland.
Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Universitätszentrum München (MUM), LMU Klinikum, LMU München, München, Deutschland.
Orthopadie (Heidelb). 2024 Jul;53(7):511-518. doi: 10.1007/s00132-024-04518-2. Epub 2024 Jun 4.
In vitro studies are an established method to determine joint kinematics for answering preclinical questions regarding the effects of new treatment options, surgical techniques or implant designs. The lack of standardized, interdisciplinary representation in the determination of joint kinematics poses a problem. In addition to representation forms such as the "neutral-zero method" or the description of movements within the three basic planes, there are other mathematical joint-specific representations of individual working groups. The International Society of Biomechanics (ISB) has already made recommendations for standardization, but most of these cannot be implemented in biomechanical in-vitro studies. The cluster has therefore set itself the goal of standardizing in-vitro test methods in order to achieve better comparability of scientific results from different working groups.
体外研究是一种既定的方法，用于确定关节运动学，以回答有关新治疗方案、手术技术或植入物设计效果的临床前问题。在关节运动学测定中缺乏标准化的、跨学科的表示方法是一个问题。除了“中立-零方法”等表示形式或三个基本平面内运动的描述外，各个工作组还有其他特定于关节的数学表示方法。国际生物力学学会（ISB）已经提出了标准化建议，但其中大多数无法在生物力学体外研究中实施。因此，该集群为自己设定了标准化体外测试方法的目标，以便不同工作组的科学结果具有更好的可比性。
