García Jorge Cea, Maraver Francisco Márquez, Rodríguez Jiménez Inmaculada, Ríos-Pena Laura, Carmen Rubio Rodríguez M
Clinical Management Unit for Obstetrics and Gynecology, University Hospital Virgen Macarena, 3 Dr Fedriani Ave., 41 009 Seville, Spain.
Clinical Management Unit for Obstetrics and Gynecology, University Hospital Virgen Macarena, 3 Dr Fedriani Ave., 41 009 Seville, Spain.
Eur J Obstet Gynecol Reprod Biol. 2024 Aug;299:43-53. doi: 10.1016/j.ejogrb.2024.05.027. Epub 2024 May 28.
To compare the female sexual function between cervical cancer survivors and healthy women or with benign gynecological diseases.
From January 1, 2010 to January 31, 2019, a case-control study was conducted to compare the female sexual function of 106 cervical cancer survivors from a tertiary hospital and 185 women admitted to a gynecological outpatient clinic from the same health area for a routine gynecological examination (n=46) or for a benign gynecological disorder (symptomatic, n=113; asymptomatic, n=26). We prospectively assessed the female sexual function using the Female Sexual Function Index (FSFI). For the contrastive analysis hypothesis, we employed R statistical software.
Cervical cancer survivors reported lower sexual activity rates than controls, in general, did (47.12% vs. 88.65%, p=0.0001), and, particularly, compared with healthy and symptomatic controls (47.12% vs. 82.61%, p=0.003; 47.12% vs. 87.61%, p=0.0001, respectively). Sixty and fifty-eight hundredths percent of the cervical cancer survivors experienced female sexual dysfunction, mainly due to hypoactive sexual desire (93.27%). Female sexual dysfunction was diagnosed in 64.32% of the controls, with sexual arousal disorders being the most common diagnosis (44.86%). Compared with controls, cervical cancer survivors exhibited considerably lower FSFI total scores and in sexual desire and lubrication domains (p <0.000; p <0.0001; p=0.023).
Cervical cancer survivors had worse female sexual function and less sexual activity than controls did, although scores in both groups were in range of FSD. Rates of female sexual dysfunction were similar across cervical cancer survivors and controls, with hypoactive sexual desire and sexual arousal disorders as the most common diagnoses, respectively.
比较宫颈癌幸存者与健康女性或患有良性妇科疾病的女性的性功能。
2010年1月1日至2019年1月31日，进行了一项病例对照研究，比较了一家三级医院的106名宫颈癌幸存者与来自同一健康区域的妇科门诊的185名女性的性功能，这些女性因常规妇科检查（n = 46）或患有良性妇科疾病（有症状，n = 113；无症状，n = 26）而入院。我们使用女性性功能指数（FSFI）对女性性功能进行前瞻性评估。对于对比分析假设，我们使用了R统计软件。
总体而言，宫颈癌幸存者报告的性活动率低于对照组（47.12%对88.65%，p = 0.0001），特别是与健康对照组和有症状对照组相比（分别为47.12%对82.61%，p = 0.003；47.12%对87.61%，p = 0.0001）。60.58%的宫颈癌幸存者存在女性性功能障碍，主要原因是性欲减退（93.27%）。64.32%的对照组被诊断为女性性功能障碍，其中性唤起障碍是最常见的诊断（44.86%）。与对照组相比，宫颈癌幸存者的FSFI总分以及性欲和润滑领域的得分显著更低（p <0.000；p <0.0001；p = 0.023）。
宫颈癌幸存者的女性性功能比对照组更差，性活动更少，尽管两组的得分都在性功能障碍范围内。宫颈癌幸存者和对照组的女性性功能障碍发生率相似，最常见的诊断分别是性欲减退和性唤起障碍。
