超声内镜引导下细针穿刺对腹膜病变的诊断价值

Diagnostic Value of Ultrasound Endoscopy-Guided Fine-Needle Aspiration for Peritoneal Lesions.

作者信息

Wu Wei, Qian Ming-Jie, Xu Li-Ming, Huang Jia-Liang, Xu Long-Jiang, Ye Zhen-Yu, Hu Duan-Min, Cheng Gui-Lian

出版信息

Altern Ther Health Med. 2025 Sep;31(5):136-140.

Abstract

BACKGROUND

Peritoneal lesions present diagnostic challenges, necessitating precise imaging techniques. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) offers a promising approach for accurate diagnosis, aiding in optimal patient management and treatment planning.

OBJECTIVE

This study aims to assess the diagnostic efficacy of EUS-FNA in peritoneal lesions to offer insight in guiding optimal patient management.

METHODS

A prospective observational study was conducted, and a total of 58 patients who underwent EUS-FNA of the peritoneum at our hospital between October 2021 and November 2021 were included. The ultrasound diagnostic instrument facilitated puncture guidance, with 2-5 punctures performed in various parts of the selected peritoneal lesion areas. The analysis encompassed evaluating the sensitivity, specificity, positive predictive value, and negative predictive value of biopsy for diagnosing peritoneal-associated lesions, alongside assessing the number of punctures, puncture satisfaction, and incidence of postoperative complications.

RESULTS

The included patients undergoing EUS-FNA revealed that 41 (70.69%) had malignant lesions, while 17 (29.31%) presented with benign lesions. The diagnostic accuracy of EUS-FNA for peritoneal lesions was determined to be 94.83%, with a diagnostic sensitivity of 97.30% for malignant tumors, specificity of 90.48%, positive predictive value of 94.74%, and negative predictive value of 95%. Lesions exhibited a size range of 2.5cm × 2.9cm to 15.2cm × 9.8cm. Each patient underwent 2-5 punctures (3.3 ± 1.4), with a puncture satisfaction rate of 96.55%. The incidence of postoperative complications following EUS-FNA was found to be 3.45%.

CONCLUSION

EUS-FNA exhibits substantial diagnostic utility for peritoneal-related lesions, marked by exceptional accuracy, sensitivity, specificity, and favorable safety. Its clinical adoption is warranted, promising improved patient care and management.

摘要

背景

腹膜病变带来诊断挑战，需要精确的成像技术。内镜超声引导下细针穿刺抽吸术（EUS-FNA）为准确诊断提供了一种有前景的方法，有助于优化患者管理和治疗规划。

目的

本研究旨在评估EUS-FNA对腹膜病变的诊断效能，为指导最佳患者管理提供见解。

方法

进行了一项前瞻性观察性研究，纳入了2021年10月至2021年11月期间在我院接受腹膜EUS-FNA的58例患者。超声诊断仪辅助穿刺引导，在选定的腹膜病变区域的不同部位进行2至5次穿刺。分析包括评估活检诊断腹膜相关病变的敏感性、特异性、阳性预测值和阴性预测值，同时评估穿刺次数、穿刺满意度和术后并发症发生率。

结果

接受EUS-FNA的纳入患者显示，41例（70.69%）有恶性病变，而17例（29.31%）为良性病变。EUS-FNA对腹膜病变的诊断准确性为94.83%，对恶性肿瘤的诊断敏感性为97.30%，特异性为90.48%，阳性预测值为94.74%，阴性预测值为95%。病变大小范围为2.5cm×2.9cm至15.2cm×9.8cm。每位患者进行2至5次穿刺（3.3±1.4），穿刺满意率为96.55%。EUS-FNA术后并发症发生率为3.45%。