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无代码机器学习:在锁骨骨折分类用例上验证该方法。

No code machine learning: validating the approach on use-case for classifying clavicle fractures.

机构信息

Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, USA; Mass General Brigham AI, USA.

Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, USA; Mass General Brigham AI, USA.

出版信息

Clin Imaging. 2024 Aug;112:110207. doi: 10.1016/j.clinimag.2024.110207. Epub 2024 May 31.

Abstract

PURPOSE

We created an infrastructure for no code machine learning (NML) platform for non-programming physicians to create NML model. We tested the platform by creating an NML model for classifying radiographs for the presence and absence of clavicle fractures.

METHODS

Our IRB-approved retrospective study included 4135 clavicle radiographs from 2039 patients (mean age 52 ± 20 years, F:M 1022:1017) from 13 hospitals. Each patient had two-view clavicle radiographs with axial and anterior-posterior projections. The positive radiographs had either displaced or non-displaced clavicle fractures. We configured the NML platform to automatically retrieve the eligible exams using the series' unique identification from the hospital virtual network archive via web access to DICOM Objects. The platform trained a model until the validation loss plateaus. Once the testing was complete, the platform provided the receiver operating characteristics curve and confusion matrix for estimating sensitivity, specificity, and accuracy.

RESULTS

The NML platform successfully retrieved 3917 radiographs (3917/4135, 94.7 %) and parsed them for creating a ML classifier with 2151 radiographs in the training, 100 radiographs for validation, and 1666 radiographs in testing datasets (772 radiographs with clavicle fracture, 894 without clavicle fracture). The network identified clavicle fracture with 90 % sensitivity, 87 % specificity, and 88 % accuracy with AUC of 0.95 (confidence interval 0.94-0.96).

CONCLUSION

A NML platform can help physicians create and test machine learning models from multicenter imaging datasets such as the one in our study for classifying radiographs based on the presence of clavicle fracture.

摘要

目的

我们创建了一个无代码机器学习(NML)平台的基础设施,供非编程医生创建 NML 模型。我们通过创建一个用于分类有无锁骨骨折的 X 光片的 NML 模型来测试该平台。

方法

我们的这项经机构审查委员会批准的回顾性研究纳入了来自 13 家医院的 2039 名患者(平均年龄 52 ± 20 岁,女性:男性为 1022:1017)的 4135 例锁骨 X 光片。每位患者均有两张锁骨 X 光片,分别为轴位和前后位。阳性 X 光片既有移位性骨折,也有无移位性骨折。我们通过网络访问 DICOM 对象,使用医院虚拟网络存档中的系列唯一标识来配置 NML 平台,以自动检索符合条件的检查。该平台会在验证损失达到稳定水平后继续训练模型。一旦测试完成,该平台将提供受试者工作特征曲线和混淆矩阵,以估计敏感性、特异性和准确性。

结果

NML 平台成功检索到 3917 张 X 光片(3917/4135,94.7%),并对其进行解析,以创建一个用于机器学习分类器的模型,其中 2151 张 X 光片用于训练,100 张 X 光片用于验证,1666 张 X 光片用于测试数据集(772 张 X 光片有锁骨骨折,894 张 X 光片无锁骨骨折)。该网络识别锁骨骨折的敏感度为 90%,特异度为 87%,准确性为 88%,曲线下面积(AUC)为 0.95(置信区间 0.94-0.96)。

结论

NML 平台可帮助医生从多中心成像数据集(如本研究中的数据集)中创建和测试机器学习模型,以便根据锁骨骨折的存在对 X 光片进行分类。

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