Department of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Department of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Asian J Psychiatr. 2024 Aug;98:104070. doi: 10.1016/j.ajp.2024.104070. Epub 2024 May 13.
Sleep is a vital restorative process that has occupied our curiosity for millennia. Despite our longstanding research efforts, the biology of sleep and its connection to mental states remains enigmatic. Unsurprisingly, sleep and wakefulness, the fundamental processes between which our mental states oscillate, are inseparable from our physical and mental health. Thus, clinical consideration of sleep impairments warrants a transdiagnostic approach whilst appropriately acknowledging that certain individual disorders (e.g. depression, schizophrenia) may have somewhat distinct sleep disturbances. Moreover, our knowledge of the anatomy and physiology of sleep regulation-albeit limited-forms the foundation for current treatments for sleep difficulties. This pictorial article overviews the core concepts and future of sleep neuroscience and mental state biology for trainees and practitioners in psychiatry and related professions.
睡眠是一种至关重要的恢复过程，数千年来一直引起我们的好奇。尽管我们进行了长期的研究努力，但睡眠的生物学及其与精神状态的联系仍然是神秘的。毫不奇怪，睡眠和觉醒是我们的精神状态在其间波动的基本过程，它们与我们的身心健康是不可分割的。因此，对睡眠障碍的临床考虑需要一种跨诊断的方法，同时适当认识到某些特定的障碍（如抑郁症、精神分裂症）可能有不同程度的睡眠障碍。此外，我们对睡眠调节的解剖学和生理学的认识——尽管有限——构成了当前治疗睡眠困难的基础。这篇图片文章概述了睡眠神经科学和精神状态生物学的核心概念和未来，供精神病学和相关专业的学员和从业者参考。
