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以患者为中心的教科书式结局测量指标能够有效地鉴别当代择期开放腹主动脉瘤修复质量。

A patient-centered textbook outcome measure effectively discriminates contemporary elective open abdominal aortic aneurysm repair quality.

机构信息

Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

Division of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL.

出版信息

J Vasc Surg. 2024 Oct;80(4):1071-1081.e5. doi: 10.1016/j.jvs.2024.05.052. Epub 2024 Jun 3.

Abstract

BACKGROUND

There is persistent controversy surrounding the merit of surgical volume benchmarks being used solely as a sufficient proxy for assessing the quality of open abdominal aortic aneurysm (AAA) repair. Importantly, operative volume quotas may fail to reflect a more nuanced and comprehensive depiction of surgical outcomes most relevant to patients. Accordingly, we herein propose a patient-centered textbook outcome (TO) for AAA repair that is analogous to other large magnitude extirpative operations performed in other surgical specialties, and test its feasibility to discriminate hospital performance using Society for Vascular Surgery (SVS) volume guidelines.

METHODS

All elective open infrarenal AAA repairs (OAR) in the SVS-Vascular Quality Initiative were examined (2009-2022). The primary end point was a TO, defined as a composite of no in-hospital complication or reintervention/reoperation, length of stay of ≤10 days, home discharge, and 1-year survival rates. The discriminatory ability of the TO measure was assessed by comparing centers that did or did not meet the SVS annual OAR volume threshold recommendation (high volume ≥10 OARs/year; low volume <10 OARs/year). Logistic regression and multivariable models adjusted for patient and procedure-related differences.

RESULTS

A total of 9657 OARs across 198 centers were analyzed (mean age, 69.5 ± 8.4 years; female, 26%; non-White, 12%). A TO was identified in 44% (n = 4293) of the overall cohort. The incidence of individual TO components included no in-hospital complication (61%), no in-hospital reintervention or reoperation (92%), length of stay of ≤10 days (78%), home discharge (76%), and 1-year survival (91%). Median annual center volume was 6 (interquartile range, 3-10) and a majority of centers did not meet the SVS volume suggested threshold (<10 OARs/year, n = 148 [74%]). However, most patients (6265 of 9657 [65%]) underwent OAR in high-volume hospitals. When comparing high- and low-volume centers, a TO was more likely to occur in high-volume institutions: ≥10 OARs/year (46%) vs <10 OARs/year (42%; P = .0006). The association of a protective effect for higher center volume remained after risk adjustment (odds ratio, 1.1; 95% confidence interval, 1.05-1.26; P = .003).

CONCLUSIONS

TOs for elective OAR reflect a more nuanced and comprehensive patient centered proxy to measure care delivery, consistent with other surgical specialties. Surprisingly, a TO was achieved in <50% of elective AAA cases nationally. Although the likelihood of a TO seems to correlate with SVS center volume recommendations, it more importantly reflects elements which may be prioritized by patients and thus offers insights into further improving real-world AAA care.

摘要

背景

围绕着手术量基准是否可以仅作为评估开放式腹主动脉瘤(AAA)修复质量的充分替代指标,一直存在争议。重要的是,手术量定额可能无法反映与患者最相关的更精细和全面的手术结果描述。因此,我们在此提出了一种以患者为中心的 AAA 修复教科书结局(TO),类似于其他外科专业进行的其他大切除手术,并根据血管外科学会(SVS)的体积指南,测试其区分医院绩效的可行性。

方法

对 SVS-血管质量倡议中的所有择期开放式肾下 AAA 修复(OAR)进行了检查(2009-2022 年)。主要终点是 TO,定义为无院内并发症或再干预/再手术、住院时间≤10 天、出院回家和 1 年生存率的复合指标。通过比较符合或不符合 SVS 年度 OAR 体积阈值推荐(高容量≥10 个 OAR/年;低容量<10 个 OAR/年)的中心,评估 TO 测量的区分能力。使用逻辑回归和多变量模型调整了患者和手术相关的差异。

结果

共分析了 198 个中心的 9657 例 OAR(平均年龄 69.5±8.4 岁;女性 26%;非白人 12%)。总体队列中 44%(n=4293)确定了 TO。单个 TO 组成部分的发生率包括无院内并发症(61%)、无院内再干预或再手术(92%)、住院时间≤10 天(78%)、出院回家(76%)和 1 年生存率(91%)。中心的年平均容量为 6(四分位距,3-10),大多数中心不符合 SVS 建议的体积阈值(<10 个 OAR/年,n=148[74%])。然而,大多数患者(9657 例中的 6265 例[65%])在高容量医院接受 OAR。在比较高容量和低容量中心时,高容量机构更有可能发生 TO:≥10 个 OAR/年(46%)与<10 个 OAR/年(42%;P=0.0006)。在风险调整后,较高中心容量的保护作用仍然存在(优势比,1.1;95%置信区间,1.05-1.26;P=0.003)。

结论

用于择期 OAR 的 TO 反映了一种更精细和全面的以患者为中心的替代指标,用于衡量护理提供情况,与其他外科专业一致。令人惊讶的是,全国范围内只有<50%的择期 AAA 病例实现了 TO。尽管 TO 的可能性似乎与 SVS 中心容量建议相关,但它更重要的是反映了可能被患者优先考虑的因素,从而为进一步改善真实世界的 AAA 护理提供了思路。

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