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三叉神经痛的神经内松解术:日本单机构初步经验。

Internal Neurolysis for Trigeminal Neuralgia: A Preliminary Single-institution Experience in Japan.

机构信息

Department of Neurosurgery, Mitsui Memorial Hospital.

出版信息

Neurol Med Chir (Tokyo). 2024 Jul 15;64(7):261-265. doi: 10.2176/jns-nmc.2023-0285. Epub 2024 Jun 5.

Abstract

Internal neurolysis (IN) is a surgical procedure in which the trigeminal fibers are separated between the pons and porus trigeminus to relieve trigeminal neuralgia (TN). Recent investigations revealed that the number of nerve bundles made by IN varies, and immediate postoperative hypesthesia exceeded 90% and pain control rate at 1 year was 77%-93.5%. We present the preliminary experience of 18 patients who underwent IN for TN between June 2020 and June 2022. The Barrow Neurological Institute pain scale (BNI-PS) was recorded preoperatively and in June 2023, and the Barrow Neurological Institute hypesthesia scale (BNI-HS) was recorded preoperatively, immediate postoperatively and in June 2023. Intraoperatively, the number of bundles made by IN was reviewed. Preoperative BNI-PS ranged between VI and V. Two patients experienced BNI-HS II due to percutaneous procedure prior to IN. Intraoperatively, 3 bundles were made by IN in 7 patients, 4 bundles in 5, and 5 bundles in 6. Immediate postoperative BNI-HS I was recorded in 6 patients and II in 12 (66.7%). The last follow-up revealed that BNI-PS I and II were recorded in 13 patients (72.2%) and BNI-HS I and II in 6 patients, respectively. Our results demonstrated that the rates of immediate postoperative hypesthesia (66.7%) and pain control (72.2%) at 1 year or later were below those of previous reports. Therefore, we are currently combing to make at least 6 bundles. Detailed surgical technique and cardiac reflex alerts during the procedure are described.

摘要

神经内松解术(IN)是一种将三叉神经纤维在脑桥和三叉神经孔之间分离的手术,用于缓解三叉神经痛(TN)。最近的研究表明,IN 所分离的神经束数量不同,术后即刻的感觉减退超过 90%,1 年后的疼痛控制率为 77%-93.5%。我们报告了 2020 年 6 月至 2022 年 6 月期间接受 IN 治疗 TN 的 18 例患者的初步经验。术前和 2023 年 6 月记录了巴罗神经病学研究所疼痛量表(BNI-PS),术前、术后即刻和 2023 年 6 月记录了巴罗神经病学研究所感觉减退量表(BNI-HS)。术中回顾了 IN 所分离的神经束数量。术前 BNI-PS 范围为 VI 至 V。2 例患者在 IN 之前因经皮治疗出现 BNI-HS II。术中,7 例患者分离出 3 束,5 例患者分离出 4 束,6 例患者分离出 5 束。6 例患者术后即刻记录为 BNI-HS I,12 例(66.7%)为 BNI-HS II。末次随访时,13 例(72.2%)患者记录为 BNI-PS I 和 II,6 例(33.3%)患者记录为 BNI-HS I 和 II。我们的结果表明,术后即刻感觉减退(66.7%)和 1 年或更长时间后的疼痛控制(72.2%)的比率低于先前的报告。因此,我们目前正在努力分离至少 6 束神经。详细的手术技术和术中的心反射警报也进行了描述。

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