The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Hospital, Anhui Provincial Stereotactic Neurological Institute, Anhui Provincial Key Laboratory of Brain Function and Disease - Neurosurgery, Anhui, Republic of China.
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Anhui provincial hospital - Neurosurgery, Anhui, Republic of China.
J Neurol Surg A Cent Eur Neurosurg. 2021 Jul;82(4):364-368. doi: 10.1055/s-0041-1723809. Epub 2021 Apr 12.
Trigeminal neuralgia is a common neurologic disease that seriously impacts a patient's quality of life. We retrospectively investigated the efficacy and safety of internal neurolysis (nerve combing) for trigeminal neuralgia without vascular compression.
This study was a retrospective review of all patients with trigeminal neuralgia who were admitted between January 2014 and February 2019. A subgroup of 36 patients had no vascular compression at surgery and underwent internal neurolysis. Chart review and postoperative follow-up were performed to assess the overall outcomes of internal neurolysis.
Thirty-six patients were identified, with a mean age of 44.89 ± 7.90 (rang: 31-65) years and a disease duration of 5.19 ± 2.61 years. The immediate postoperative pain relief (Barrow Neurological Institute [BNI] pain score of I or II) rate was 100%. The medium- to long-term pain relief rate was 91.7%. Three patients experienced recurrence. Facial numbness was the primary postoperative complication. Four patients with a score of III on the BNI numbness scale immediately after surgery had marked improvement at 6 months. No serious complications occurred.
Internal neurolysis is a safe and effective treatment for trigeminal neuralgia without vascular compression or clear responsible vessels.
三叉神经痛是一种常见的神经疾病，严重影响患者的生活质量。我们回顾性研究了无血管压迫的三叉神经痛的神经内松解（神经梳理）的疗效和安全性。
这项研究回顾性分析了 2014 年 1 月至 2019 年 2 月期间所有因三叉神经痛入院的患者。36 例患者术中无血管压迫，行神经内松解术。通过图表回顾和术后随访评估神经内松解的总体疗效。
共纳入 36 例患者，平均年龄为 44.89 ± 7.90 岁（范围：31-65 岁），病程为 5.19 ± 2.61 年。术后即刻疼痛缓解率（巴罗神经研究所[BNI]疼痛评分 I 或 II 级）为 100%。中-长期疼痛缓解率为 91.7%。3 例患者复发。面部麻木是主要的术后并发症。术后即刻 BNI 麻木评分 III 级的 4 例患者在 6 个月时明显改善。无严重并发症发生。
神经内松解术是一种安全有效的治疗无血管压迫或明确责任血管的三叉神经痛的方法。
