Institute for Evolution and Biodiversity, University of Münster, 48149 Münster, Germany.
Cologne Center for Genomics (CCG), Medical Faculty, University of Cologne, 50931 Cologne, Germany.
Genome Res. 2024 Jul 23;34(6):863-876. doi: 10.1101/gr.278392.123.
Eusocial Hymenoptera have the highest recombination rates among all multicellular animals studied so far, but it is unclear why this is and how this affects the biology of individual species. A high-resolution linkage map for the ant corroborates genome-wide high recombination rates reported for ants (8.1 cM/Mb). However, recombination is locally suppressed in regions that are enriched with TEs, that have strong haplotype divergence, or that show signatures of epistatic selection in The results do not support the hypotheses that high recombination rates are linked to phenotypic plasticity or to modulating selection efficiency. Instead, genetic diversity and the frequency of structural variants correlate positively with local recombination rates, potentially compensating for the low levels of genetic variation expected in haplodiploid social Hymenoptera with low effective population size. Ultimately, the data show that recombination contributes to within-population polymorphism and to the divergence of the lineages within .
社会性膜翅目昆虫的重组率在迄今所有研究过的多细胞动物中是最高的，但目前尚不清楚为什么会这样，以及这对各物种的生物学有何影响。 对蚂蚁的高分辨率连锁图谱证实了之前报道的蚂蚁全基因组高重组率（8.1 cM/Mb）。然而，在富含转座元件（TEs）的区域、具有强烈单倍型分化的区域或表现出上位性选择特征的区域，重组受到局部抑制。结果并不支持以下假说：高重组率与表型可塑性或调节选择效率有关。相反，遗传多样性和结构变异的频率与局部重组率呈正相关，这可能补偿了由于有效种群大小低而导致的单倍二倍体社会性膜翅目昆虫中遗传变异水平低的情况。最终，数据表明重组有助于种群内多态性的形成，以及 内谱系的分化。
