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皮马印第安人白内障摘除术的发病率。糖尿病作为一个风险因素。

Incidence of cataract extraction in Pima Indians. Diabetes as a risk factor.

作者信息

Schwab I R, Dawson C R, Hoshiwara I, Szuter C F, Knowler W C

出版信息

Arch Ophthalmol. 1985 Feb;103(2):208-12. doi: 10.1001/archopht.1985.01050020060020.

DOI:10.1001/archopht.1985.01050020060020
PMID:3883967
Abstract

The incidence of visually disabling cataract was estimated by the rate of first cataract extraction in a population of Pima Indians in Arizona. The annual age-specific rates of cataract surgery (first and second eyes) were 3.7 to 5.9 times as high as the estimated US rates. Diabetes was a strong risk factor for first cataract surgery in all age and sex groups except in men aged 75 to 84 years. Overall, with age and sex controlled, the rate of first cataract surgery was 2.2 times as high (95% confidence interval, 1.3 to 3.9) in diabetic as in nondiabetic subjects. Cataract surgery was related to the duration and type of treatment of diabetes. Insulin-treated diabetics had about five times the rate of those with normal glucose tolerance. The rate of cataract surgery was lowest in subjects with normal glucose tolerance, somewhat higher in those with impaired glucose tolerance, and even higher with increasing duration of diabetes.

摘要

通过对亚利桑那州皮马印第安人群体中首次白内障摘除率来估算致盲性白内障的发病率。白内障手术(单眼及双眼首次手术)的年龄别年发病率是美国估算发病率的3.7至5.9倍。除75至84岁男性外,糖尿病是所有年龄和性别组首次白内障手术的一个重要危险因素。总体而言,在控制年龄和性别后,糖尿病患者首次白内障手术率是非糖尿病患者的2.2倍(95%置信区间为1.3至3.9)。白内障手术与糖尿病的病程和治疗类型有关。接受胰岛素治疗的糖尿病患者的手术率约为糖耐量正常者的五倍。白内障手术率在糖耐量正常的受试者中最低,糖耐量受损者略高,且随着糖尿病病程延长而更高。

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