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急性 A 型主动脉夹层伴冠状动脉旁路移植术的延迟治疗。

Delayed management of acute type A aortic dissection with concomitant coronary artery bypass graft.

机构信息

Department of Cardiothoracic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

出版信息

J Cardiothorac Surg. 2024 Jun 5;19(1):320. doi: 10.1186/s13019-024-02821-9.

DOI:10.1186/s13019-024-02821-9
PMID:38840211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11151597/
Abstract

BACKGROUND

Pre-operative coronary angiography and concomitant, planned coronary artery bypass are infrequently performed with type A aortic dissection repair. We present a case in which pre-operative coronary computed tomography angiography was appropriate, and subsequent dissection repair and concomitant coronary artery bypass were successfully performed.

CASE PRESENTATION

The patient is a 58-year-old male with heart failure with preserved ejection fraction, renal insufficiency, hypertension, obesity, and smoking history, who presented with a three-to-four-day history of persistent back pain, worsening exertional dyspnea, and orthopnea, as well as a two-to-three month history of dyspnea, lower extremity edema, and intermittent angina. He was diagnosed with an acute type A aortic dissection and anti-impulse control was initiated. However, repair was delayed in order to allow apixaban to metabolize and decrease the risk of bleeding, as the patient was approximately six days post-dissection, without malperfusion, with a well-controlled blood pressure on anti-impulse therapy, and had received five days of anticoagulation. During this time, coronary computed tomography angiography was performed to assess the need for concomitant revascularization and showed coronary artery disease. Ascending aorta hemiarch replacement with aortic valve resuspension, two-vessel coronary artery bypass grafting, and left atrial appendage clipping were performed successfully.

CONCLUSIONS

Pre-operative imaging can be considered in a select group of acute type A aortic dissections that present without malperfusion, and with well-controlled blood pressure on anti-impulse/negative inotropic therapy.

摘要

背景

在进行 A 型主动脉夹层修复术时,通常不会同时进行术前冠状动脉造影和计划中的冠状动脉旁路移植术。我们报告了一例患者,该患者术前进行了冠状动脉计算机断层血管造影检查,随后成功进行了夹层修复和同期冠状动脉旁路移植术。

病例介绍

患者为 58 岁男性,有心力衰竭伴射血分数保留、肾功能不全、高血压、肥胖和吸烟史,因持续背痛、进行性呼吸困难和端坐呼吸以及呼吸困难、下肢水肿和间歇性心绞痛病史 3-4 天就诊。患者被诊断为急性 A 型主动脉夹层,开始进行抗冲动治疗。然而,为了让阿哌沙班代谢并降低出血风险,修复被推迟,因为患者大约在夹层后 6 天,没有灌注不良,在抗冲动治疗下血压得到良好控制,并且已经接受了 5 天的抗凝治疗。在此期间,进行了冠状动脉计算机断层血管造影检查以评估同期血运重建的需要,结果显示存在冠状动脉疾病。成功进行了升主动脉半弓置换、双支冠状动脉旁路移植术和左心耳夹闭。

结论

对于无灌注不良且在抗冲动/负性肌力治疗下血压得到良好控制的急性 A 型主动脉夹层,可以考虑术前影像学检查。

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How should we manage type A aortic dissection?我们应该如何处理A型主动脉夹层?
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