Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK.
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK.
Analyst. 2024 Jun 24;149(13):3513-3517. doi: 10.1039/d4an00617h.
Live chicken egg embryos offer new opportunities for evaluation and continuous monitoring of tumour growth for studies compared to traditional rodent models. Here, we report the first use of surface enhanced Raman scattering (SERS) mapping and surface enhanced spatially offset Raman scattering (SESORS) for the detection and localisation of targeted gold nanoparticles in live chicken egg embryos bearing a glioblastoma tumour.
活鸡胚胎为肿瘤生长的研究提供了比传统啮齿动物模型更具优势的评估和持续监测机会。在这里，我们报告了首次使用表面增强拉曼散射（SERS）图谱和表面增强空间偏移拉曼散射（SESORS）来检测和定位携带神经胶质瘤肿瘤的活鸡胚胎中的靶向金纳米粒子。
