College of Stomatology, Hangzhou Normal University, Hangzhou, Zhejiang Province, China.
Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.
PLoS One. 2024 Jun 6;19(6):e0305010. doi: 10.1371/journal.pone.0305010. eCollection 2024.
This study aims to examine the association between the Weight-adjusted Waist Circumference Index (WWI) and the prevalence of periodontitis, providing novel evidence on the link between central obesity and periodontal health.
A cross-sectional study was conducted with 10,289 participants enrolled from NHANES 2009 to 2014. WWI was calculated by dividing waist circumference by the square root of weight. We employed a multivariate logistic regression model and smoothed curve fitting method to evaluate the relationship between WWI and periodontitis. We also compared different subgroups and analyzed the interaction effects.
A significant positive association between WWI and periodontitis was observed in 10,289 participants aged ≥30 (OR: 1.20, 95% CI: 1.12-1.28). Upon categorizing WWI into quartiles, the top quartile group exhibited a 27% increased prevalence of periodontitis compared to the bottom quartile (OR: 1.27, 95% CI: 1.10-1.46; P for trend = 0.001). Among individuals aged 30 to 60, the strength of this positive correlation is more pronounced than in those aged 60 and above.
WWI demonstrates a positive correlation with periodontitis with a particularly pronounced impact on moderate periodontitis, suggesting its potential to improve periodontitis prevention in a broad population.
本研究旨在探讨体重调整腰围指数（Weight-adjusted Waist Circumference Index，WWI）与牙周炎患病率之间的关联，为中心性肥胖与牙周健康之间的关系提供新的证据。
采用 2009 年至 2014 年 NHANES 中的 10289 名参与者进行横断面研究。通过将腰围除以体重的平方根来计算 WWI。我们采用多变量逻辑回归模型和平滑曲线拟合方法来评估 WWI 与牙周炎之间的关系。我们还比较了不同亚组并分析了交互作用效应。
在≥30 岁的 10289 名参与者中，观察到 WWI 与牙周炎之间存在显著的正相关关系（OR：1.20，95%CI：1.12-1.28）。将 WWI 分为四等份后，与底部四分之一组相比，顶部四分之一组的牙周炎患病率增加了 27%（OR：1.27，95%CI：1.10-1.46；趋势 P 值=0.001）。在 30 至 60 岁的人群中，这种正相关关系的强度比 60 岁及以上的人群更为明显。
WWI 与牙周炎呈正相关，且对中度牙周炎的影响更为显著，提示其有可能改善广泛人群的牙周炎预防效果。
