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手术延误超过 12 小时与髋部骨折死亡率增加相关。

Delay to surgery beyond 12 hours is associated with increased hip fracture mortality.

机构信息

NWAFT, Peterborough, UK.

Bedfordshire Hospitals NHS Foundation Trust, Bedford, UK.

出版信息

Eur J Orthop Surg Traumatol. 2024 Aug;34(6):2973-2980. doi: 10.1007/s00590-024-03997-5. Epub 2024 Jun 7.

DOI:10.1007/s00590-024-03997-5
PMID:38844565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11377486/
Abstract

PURPOSE

Time to surgery from admission is one of the few variables known to influence outcome after a hip fracture. We reviewed our hip fracture database to determine correlation between delays to surgery and mortality in our elderly hip fracture population.

METHODS

Data on all hip fracture patients admitted to a large district hospital were prospectively collected between January 1989 and August 2021. Time of the injury, time of admission and time of surgery were recorded. Patients over 60 years old with a hip fracture requiring operative management were included. Patients with pathological fractures, those managed conservatively, and patients delayed for medical reasons were excluded. Surgical timing categories were divided into; under 12 h, 12-24 h, 24-72 h and over 72 h.

RESULTS

Time from admission to surgery was recorded for 10,659 patients, of these time of fall was available for 10,346 patients. Mean age was 82.2 years (sd 8.39) for the cohort and 30 day mortality was 6.20%. Odds of 30-day mortality was 1.43 (CI 1.057-1.988, p = 0.025) for delay to surgery from admission of over 12 h compared to under 12 h. Odds ratios for 30-day mortality were not significant at any other time threshold. The odds of 30-day mortality for delay to surgery from time of fall were 1.550 (CI 1.026-2.459, p = 0.048) at the 12 h threshold.

CONCLUSION

This is the largest prospective study to date in elderly patients with hip fractures demonstrating a statistically significant increase in 30-day mortality with a delay to surgery over 12 h.

摘要

目的

从入院到手术的时间是影响髋部骨折患者预后的少数几个已知变量之一。我们回顾了我们的髋部骨折数据库,以确定我们的老年髋部骨折患者群体中手术延迟与死亡率之间的相关性。

方法

1989 年 1 月至 2021 年 8 月期间,我们前瞻性地收集了所有在一家大型地区医院就诊的髋部骨折患者的数据。记录受伤时间、入院时间和手术时间。纳入年龄在 60 岁以上、需要手术治疗的髋部骨折患者。排除病理性骨折、保守治疗患者以及因医疗原因延迟手术的患者。手术时间类别分为:12 小时内、12-24 小时、24-72 小时和 72 小时以上。

结果

我们记录了 10659 名患者的从入院到手术的时间,其中 10346 名患者的跌倒时间可查。该队列的平均年龄为 82.2 岁(标准差 8.39),30 天死亡率为 6.20%。与 12 小时内相比,入院后手术延迟超过 12 小时的 30 天死亡率的比值比为 1.43(95%置信区间 1.057-1.988,p=0.025)。在任何其他时间阈值下,30 天死亡率的比值比均无显著意义。从跌倒到手术的延迟时间的 30 天死亡率的比值比为 1.550(95%置信区间 1.026-2.459,p=0.048),在 12 小时阈值时。

结论

这是迄今为止在老年髋部骨折患者中进行的最大前瞻性研究,表明手术延迟超过 12 小时与 30 天死亡率显著增加相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/0e891e78dfb4/590_2024_3997_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/0fa241a69e22/590_2024_3997_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/b28d37667be1/590_2024_3997_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/0e891e78dfb4/590_2024_3997_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/0fa241a69e22/590_2024_3997_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/b28d37667be1/590_2024_3997_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca47/11377486/0e891e78dfb4/590_2024_3997_Fig3_HTML.jpg

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