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椎间盘源性坐骨神经痛硬膜外类固醇注射治疗结局的预测因素:德尔菲共识研究。

Predictors of outcome following an epidural steroid injection for disc-related sciatica: a Delphi consensus study.

机构信息

School of Medicine, Keele University, Keele, United Kingdom.

Midlands Partnership University NHS Foundation Trust, North Staffordshire and Stoke on Trent Integrated Musculoskeletal Service, Staffordshire, United Kingdom.

出版信息

Eur Spine J. 2024 Nov;33(11):4235-4242. doi: 10.1007/s00586-024-08342-2. Epub 2024 Jun 7.

Abstract

PURPOSE

Trial data shows modest reductions in leg pain, disability and surgery avoidance following epidural steroid injections (ESI) for severe sciatica. Despite their common use, there is no clear evidence about which patients are more likely to benefit from ESI. The aim of this study was to generate consensus on potential predictors of outcome following ESI for disc-related sciatica.

METHODS

A list of potential predictors of outcome was generated during a consensus meeting of seven experts. The items were subsequently presented in a two round on-line Delphi study to generate consensus among experts on which items are potential predictors of outcome. Consensus was defined as 70% agreement among participants.

RESULTS

Sixty-one items were generated during the consensus meeting. Of ninety experts invited to participate in the on-line Delphi study, 44 (48%) and 33 (73%) took part in rounds one and two respectively. Twenty-eight additional items suggested by participants in round one were included in round two. Overall, 14 items reached consensus reflecting domains of health, medication use, pain intensity, psychosocial factors, imaging findings and type of injection.

CONCLUSION

Based on expert consensus, items that can be routinely collected in clinical practice were identified as potential predictors of outcomes following ESI.

摘要

目的

试验数据显示,硬膜外类固醇注射(ESI)治疗严重坐骨神经痛可适度减轻腿部疼痛、残疾和手术回避。尽管它们被广泛应用,但仍缺乏明确的证据表明哪些患者更有可能从 ESI 中受益。本研究旨在就与椎间盘相关的坐骨神经痛的 ESI 后潜在的预测结果达成共识。

方法

在七位专家的共识会议上生成了一组潜在的预测结果的预测因子列表。随后,这些项目在两轮在线德尔菲研究中进行了呈现,以在专家之间就哪些项目是潜在的预测结果达成共识。共识定义为参与者之间 70%的一致。

结果

共识会议期间共生成了 61 个项目。在被邀请参加在线德尔菲研究的 90 名专家中,有 44 名(48%)和 33 名(73%)分别参加了第一轮和第二轮。第一轮参与者提出的另外 28 个项目被纳入第二轮。总体而言,有 14 个项目达成了共识,反映了健康、药物使用、疼痛强度、心理社会因素、影像学发现和注射类型等领域。

结论

基于专家共识,确定了在临床实践中可以常规收集的项目作为 ESI 后结果的潜在预测因子。

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