Second Department of Neurology, National and Kapodistrian University of Athens, School of Medicine, "Attikon" University Hospital.
Department of Vascular Surgery, "Attikon" Hospital, University of Athens, School of Medicine, Athens, Greece.
Neurologist. 2024 Sep 1;29(5):306-307. doi: 10.1097/NRL.0000000000000573.
Symptomatic carotid artery disease (CAD) represents an uncommon but treatable cause of corticobasal syndrome.
We present the clinical details and successful management of a previously healthy 77-year-old patient who presented with 1-year cognitive dysfunction, alien limb syndrome, limb kinetic apraxia, and ipsilateral cortical sensory deficit, fulfilling the criteria of the diagnosis of probable corticobasal syndrome. Imaging modalities, including magnetic resonance imaging and time-of-flight magnetic resonance angiography, revealed acute external borderzone infarcts of the right hemisphere due to symptomatic CAD causing near occlusion of the vessel. The patient underwent a right carotid endarterectomy, leading to a marked improvement in mobility and neuropsychological evaluation.
This case highlights the importance of swift diagnosis of symptomatic CAD in patients with corticobasal syndrome. Moreover, it emphasizes the efficacy of carotid endarterectomy in achieving symptom improvement in such cases.
有症状的颈动脉疾病（CAD）代表了皮质基底节综合征的一种罕见但可治疗的病因。
我们介绍了一位先前健康的 77 岁患者的临床细节和成功治疗方法，该患者出现了 1 年的认知功能障碍、异己肢体综合征、肢体运动性失用症和同侧皮质感觉缺失，符合皮质基底节综合征的可能诊断标准。成像方式，包括磁共振成像和时间飞跃磁共振血管造影术，显示由于症状性 CAD 导致血管近乎闭塞，右半球出现急性外边界区梗死。患者接受了右侧颈动脉内膜切除术，导致运动能力和神经心理学评估显著改善。
本病例强调了在皮质基底节综合征患者中迅速诊断症状性 CAD 的重要性。此外，它还强调了颈动脉内膜切除术在改善此类病例症状方面的疗效。
