预测生长激素缺乏儿童接受重组人生长激素（r-hGH）治疗后1个月内胰岛素样生长因子-1（IGF-1）变化的重要生物标志物。 - Suppr

Significant biomarkers for predicting 1-month changes in IGF-1 in growth hormone-deficient children following r-hGH therapy.

作者信息

Liu Fei, Lei NokI, Li Wunying, Zheng Yiwen, Hu Liangjian, Hu Ronggui, Lu Wenli, Huang Yu S

机构信息

Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medical, Chinese Academy of Sciences, Shanghai 201203, China.

University of Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Acta Biochim Biophys Sin (Shanghai). 2024 Jun 6;56(11):1706-1710. doi: 10.3724/abbs.2024089.

DOI:10.3724/abbs.2024089

PMID:38845532

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11733495/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a11e/11733495/71fdfa6cef96/t1.jpg

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Significant biomarkers for predicting 1-month changes in IGF-1 in growth hormone-deficient children following r-hGH therapy.预测生长激素缺乏儿童接受重组人生长激素（r-hGH）治疗后1个月内胰岛素样生长因子-1（IGF-1）变化的重要生物标志物。

Acta Biochim Biophys Sin (Shanghai). 2024 Jun 6;56(11):1706-1710. doi: 10.3724/abbs.2024089.

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J Biol Res (Thessalon). 2017 May 16;24:9. doi: 10.1186/s40709-017-0066-y. eCollection 2017 Dec.

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Eur J Endocrinol. 2016 Dec;175(6):633-643. doi: 10.1530/EJE-16-0357. Epub 2016 Sep 20.

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Ther Adv Endocrinol Metab. 2013 Apr;4(2):41-9. doi: 10.1177/2042018813484051.

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Clin Endocrinol (Oxf). 2009 Mar;70(3):429-34. doi: 10.1111/j.1365-2265.2008.03477.x. Epub 2008 Nov 8.

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Significant biomarkers for predicting 1-month changes in IGF-1 in growth hormone-deficient children following r-hGH therapy.

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