Adefila Williams Oluwatosin, Osei Isaac, Lamin Keita Modou, Wutor Baleng Mahama, Olawale Yusuf Abdulsalam, Molfa Minteh, Barjo Ousman, Omotosho Mayowa, Salaudeen Rasheed, Mackenzie Grant
Medical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine Fajara The Gambia.
Faculty of Infectious and Tropical Diseases London School of Hygiene & Tropical Medicine London UK.
Clin Case Rep. 2024 Jun 5;12(6):e9042. doi: 10.1002/ccr3.9042. eCollection 2024 Jun.
(. ), a rare opportunistic pathogen, caused sepsis in a malnourished 15-month-old African child. Early detection and appropriate antibiotics led to full recovery, highlighting the importance of robust surveillance for emerging pathogens in vulnerable populations.
While rarely causing infections, . , a non-fermenting, obligately aerobic, flagellated gram-negative bacillus, demonstrates oxidase positivity and indole negativity. Traditionally, spp is considered a low threat due to its environmental abundance and mild virulence. It is, however, a multidrug-resistant bacteria known for causing opportunistic infections in humans. . is typically associated with catheter-related bloodstream infections. The first documented case was in 1998; most cases have been reported in developed countries. We present a case of . sepsis in a malnourished child in sub-Saharan Africa. We report a case involving a 15-month-old African female who presented with symptoms and signs of protein-energy malnutrition and sepsis. The blood culture revealed .. We treated the child with the empirical first-line antibiotics per the national guidelines, intravenous ampicillin and gentamicin for a week, and the child fully recovered. This report describes a rare case of . sepsis with malnutrition in an African female child. . is an emerging pathogen causing opportunistic infections in both immunocompetent and immunocompromised patients. We report that early bacterial detection, appropriate antibiotic susceptibility and antimicrobial management based on local antibiogram data may be essential for excellent patient outcomes. Additionally, we recommend more robust surveillance to detect such rare emerging pathogens.
（某病原体名称），一种罕见的机会性病原体，在一名营养不良的15个月大非洲儿童中引起败血症。早期检测和使用适当的抗生素导致患儿完全康复，凸显了对弱势群体中新兴病原体进行有力监测的重要性。
虽然（某病原体名称）很少引起感染，但它是一种不发酵、专性需氧、有鞭毛的革兰氏阴性杆菌，氧化酶呈阳性，吲哚呈阴性。传统上，由于其在环境中广泛存在且毒力较弱，（该病原体属）被认为威胁较小。然而，它是一种已知会在人类中引起机会性感染的多重耐药细菌。（某病原体名称）通常与导管相关的血流感染有关。首例有记录的病例发生在1998年；大多数病例在发达国家被报道。我们报告了撒哈拉以南非洲一名营养不良儿童发生（某病原体名称）败血症的病例。我们报告了一例涉及一名15个月大非洲女性的病例，该患儿出现蛋白质 - 能量营养不良和败血症的症状及体征。血培养显示（某病原体名称）。我们按照国家指南用经验性一线抗生素治疗该患儿，静脉注射氨苄西林和庆大霉素一周，患儿完全康复。本报告描述了一名非洲女童发生伴有营养不良的（某病原体名称）败血症这一罕见病例。（某病原体名称）是一种在免疫功能正常和免疫功能低下患者中均引起机会性感染的新兴病原体。我们报告早期细菌检测、适当的抗生素敏感性检测以及基于当地抗菌谱数据的抗菌管理对于取得良好的患者预后可能至关重要。此外，我们建议进行更有力的监测以检测此类罕见的新兴病原体。
