• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

探索骨质疏松症中椎旁肌肉状态与骨骼健康及骨折风险之间的相互作用：关于计算机断层扫描（CT）和磁共振成像（MRI）研究的综合文献综述

Exploring the interplay between paraspinal muscular status and bone health in osteoporosis and fracture risk: a comprehensive literature review on computed tomography (CT) and magnetic resonance imaging (MRI) studies.

作者信息

Mallio Carlo A, Volterrani Claudia, Bernetti Caterina, Stiffi Massimo, Greco Federico, Beomonte Zobel Bruno

机构信息

Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Research Unit of Radiology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.

出版信息

Quant Imaging Med Surg. 2024 Jun 1;14(6):4189-4201. doi: 10.21037/qims-23-1770. Epub 2024 Apr 15.

DOI:10.21037/qims-23-1770
PMID:38846277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11151258/
Abstract

BACKGROUND AND OBJECTIVE

Computed tomography (CT) and magnetic resonance imaging (MRI) of the spine are fundamental non-invasive tools to investigate the status of the bone and soft tissue in vivo. A novel and promising approach is to investigate the quality and quantity of paraspinal muscles even beyond the clinical question. The aim of the present review is to summarize current evidence on CT and MRI about the relationship between paraspinal muscular status and bone health in osteoporosis (OP) and fracture risk.

METHODS

Literature research was carried out on September 2023 using PubMed, Scopus, and Cochrane databases.

KEY CONTENT AND FINDINGS

Research investigating the intricate interplay between musculature and bone health reveals that degenerating paraspinal muscles, characterized by shrinking and fatty infiltration, are associated with lower bone mineral density (BMD) and the development of OP. Additionally, research indicates that weaker paraspinal muscles are linked to a higher risk of fractures, including those at the spine.

CONCLUSIONS

The findings suggest that paraspinal muscle health may be a significant factor in identifying individuals at risk for OP and fractures. Further investigation is needed to explore the potential of paraspinal muscles in preventing these conditions.

摘要

背景与目的

脊柱计算机断层扫描（CT）和磁共振成像（MRI）是研究体内骨骼和软组织状况的基本无创工具。一种新颖且有前景的方法是，甚至超出临床问题范畴来研究椎旁肌肉的质量和数量。本综述的目的是总结当前关于CT和MRI的证据，以探讨骨质疏松症（OP）中椎旁肌肉状态与骨骼健康之间的关系以及骨折风险。

方法

2023年9月利用PubMed、Scopus和Cochrane数据库进行文献研究。

关键内容与发现

对肌肉组织与骨骼健康之间复杂相互作用的研究表明，以萎缩和脂肪浸润为特征的退化性椎旁肌肉与较低的骨矿物质密度（BMD）以及OP的发生有关。此外，研究表明较弱的椎旁肌肉与更高的骨折风险相关，包括脊柱骨折。

结论

研究结果表明，椎旁肌肉健康可能是识别OP和骨折风险个体的一个重要因素。需要进一步研究以探索椎旁肌肉在预防这些病症方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/6eb17f4afd26/qims-14-06-4189-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/95099f5e888a/qims-14-06-4189-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/4ff925acde2b/qims-14-06-4189-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/6eb17f4afd26/qims-14-06-4189-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/95099f5e888a/qims-14-06-4189-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/4ff925acde2b/qims-14-06-4189-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99c8/11151258/6eb17f4afd26/qims-14-06-4189-f3.jpg

相似文献

1
Exploring the interplay between paraspinal muscular status and bone health in osteoporosis and fracture risk: a comprehensive literature review on computed tomography (CT) and magnetic resonance imaging (MRI) studies.探索骨质疏松症中椎旁肌肉状态与骨骼健康及骨折风险之间的相互作用：关于计算机断层扫描（CT）和磁共振成像（MRI）研究的综合文献综述
Quant Imaging Med Surg. 2024 Jun 1;14(6):4189-4201. doi: 10.21037/qims-23-1770. Epub 2024 Apr 15.
2
Fatty infiltration of paraspinal muscles is associated with bone mineral density of the lumbar spine.脊柱旁肌肉脂肪浸润与腰椎骨密度有关。
Arch Osteoporos. 2019 Oct 15;14(1):99. doi: 10.1007/s11657-019-0639-5.
3
Associations between paraspinal muscles fatty infiltration and lumbar vertebral bone mineral density - An investigation by fast kVp switching dual-energy CT and QCT.椎旁肌脂肪浸润与腰椎骨密度的相关性——基于快速千伏切换双能CT和定量CT的研究
Eur J Radiol Open. 2022 Oct 14;9:100447. doi: 10.1016/j.ejro.2022.100447. eCollection 2022.
4
Assessment of paraspinal muscle characteristics, lumbar BMD, and their associations in routine multi-detector CT of patients with and without osteoporotic vertebral fractures.评估有和无骨质疏松性椎体骨折患者常规多排 CT 中脊柱旁肌肉特征、腰椎 BMD 及其相关性。
Eur J Radiol. 2020 Apr;125:108867. doi: 10.1016/j.ejrad.2020.108867. Epub 2020 Feb 7.
5
The association between lumbar paraspinal muscle functional cross-sectional area on MRI and regional volumetric bone mineral density measured by quantitative computed tomography.腰椎旁肌磁共振功能性横截面积与定量计算机断层扫描测量的区域性容积骨密度之间的关联。
Osteoporos Int. 2022 Dec;33(12):2537-2545. doi: 10.1007/s00198-022-06430-x. Epub 2022 Aug 6.
6
MRI‑based vertebral bone quality score is a comprehensive index reflecting the quality of bone and paravertebral muscle.基于 MRI 的椎体骨质量评分是一个综合指标，反映了骨和椎旁肌的质量。
Spine J. 2024 Mar;24(3):472-478. doi: 10.1016/j.spinee.2023.11.007. Epub 2023 Nov 21.
7
Can paraspinal muscle degeneration be a reason for refractures after percutaneous kyphoplasty? A magnetic resonance imaging observation.椎旁肌退变能否成为经皮椎体后凸成形术后再骨折的一个原因？一项磁共振成像观察研究。
J Orthop Surg Res. 2021 Aug 3;16(1):476. doi: 10.1186/s13018-021-02623-y.
8
Correlation Between Bone Mineral Density (BMD) and Paraspinal Muscle Fat Infiltration Based on QCT: A Cross-Sectional Study.基于 QCT 的骨密度（BMD）与脊柱旁肌肉脂肪浸润的相关性：一项横断面研究。
Calcif Tissue Int. 2022 Jun;110(6):666-673. doi: 10.1007/s00223-022-00944-6. Epub 2022 Jan 10.
9
Relationship between the Properties of Paraspinal Muscles and Bone Mineral Density in Osteoporotic Patients.骨质疏松症患者椎旁肌特性与骨密度的关系。
J Coll Physicians Surg Pak. 2022 Sep;32(9):1137-1142. doi: 10.29271/jcpsp.2022.09.1137.
10
An assessment of the intra- and inter-reliability of the lumbar paraspinal muscle parameters using CT scan and magnetic resonance imaging.采用 CT 扫描和磁共振成像评估腰椎旁肌参数的内信度和间信度。
Spine (Phila Pa 1976). 2011 Jun;36(13):E868-74. doi: 10.1097/BRS.0b013e3181ef6b51.

引用本文的文献

1
Comparison of paravertebral muscle thickness and fatty infiltration in patients with osteoporosis, osteopenia and normal bone mineral density: a single-blind retrospective controlled trial.骨质疏松症、骨质减少症和骨密度正常患者椎旁肌厚度与脂肪浸润的比较：一项单盲回顾性对照试验。
Eur Spine J. 2025 May 10. doi: 10.1007/s00586-025-08901-1.
2
Magnetic resonance imaging-based bone and muscle quality parameters for predicting clinical subsequent vertebral fractures after percutaneous vertebral augmentation.基于磁共振成像的骨与肌肉质量参数预测经皮椎体强化术后临床后续椎体骨折
Quant Imaging Med Surg. 2025 Feb 1;15(2):1480-1490. doi: 10.21037/qims-24-712. Epub 2025 Jan 22.

本文引用的文献

1
The association between morphological characteristics of paraspinal muscle and spinal disorders.脊柱旁肌形态特征与脊柱疾病的关系。
Ann Med. 2023;55(2):2258922. doi: 10.1080/07853890.2023.2258922. Epub 2023 Sep 18.
2
CT-Based Radiogenomics of P4HA3 Expression in Clear Cell Renal Cell Carcinoma.基于 CT 的 P4HA3 表达在透明细胞肾细胞癌中的放射组学研究。
Acad Radiol. 2024 Mar;31(3):902-908. doi: 10.1016/j.acra.2023.07.003. Epub 2023 Aug 1.
3
Fatty Degeneration of the Autochthonous Muscles Is Significantly Associated with Incidental Non-Traumatic Vertebral Body Fractures of the Lower Thoracic Spine in Elderly Patients.
老年患者自身肌肉的脂肪变性与下胸椎偶然发生的非创伤性椎体骨折显著相关。
J Clin Med. 2023 Jul 8;12(14):4565. doi: 10.3390/jcm12144565.
4
Fatty infiltration of the multifidus muscle independently increases osteoporotic vertebral compression fracture risk.多裂肌脂肪浸润独立增加骨质疏松性椎体压缩骨折风险。
BMC Musculoskelet Disord. 2023 Jun 22;24(1):508. doi: 10.1186/s12891-023-06640-2.
5
Computed tomography density changes of bone metastases after concomitant denosumab.地舒单抗治疗后骨转移的 CT 密度变化
Skeletal Radiol. 2023 Aug;52(8):1567-1575. doi: 10.1007/s00256-023-04326-3. Epub 2023 Mar 24.
6
Alteration in the Cross-sectional Area (CSA) Ratio of the Paraspinal Muscles following Vertebral Insufficiency Fractures.椎体骨质疏松性骨折后椎旁肌横截面积（CSA）比值的改变。
Indian J Radiol Imaging. 2022 Nov 24;33(1):8-11. doi: 10.1055/s-0042-1758522. eCollection 2023 Jan.
7
Quantitative Study of Vertebral Body and Paravertebral Muscle Degeneration Based on Dual-Energy Computed Tomography: Correlation With Bone Mineral Density.基于双能 CT 的椎体及椎旁肌退变的定量研究：与骨密度的相关性。
J Comput Assist Tomogr. 2023;47(1):86-92. doi: 10.1097/RCT.0000000000001388. Epub 2022 Oct 10.
8
Advanced MR Imaging for Knee Osteoarthritis: A Review on Local and Brain Effects.膝关节骨关节炎的先进磁共振成像：关于局部和脑部影响的综述
Diagnostics (Basel). 2022 Dec 24;13(1):54. doi: 10.3390/diagnostics13010054.
9
Correlation of Psoas Muscle Index with Fragility Vertebral Fracture: A Retrospective Cross-Sectional Study of Middle-Aged and Elderly Women.腰大肌指数与脆性椎体骨折的相关性：一项针对中老年女性的回顾性横断面研究。
Int J Endocrinol. 2022 Nov 2;2022:4149468. doi: 10.1155/2022/4149468. eCollection 2022.
10
Associations between Bone Mineral Density and Longitudinal Changes of Vertebral Bone Marrow and Paraspinal Muscle Composition Assessed Using MR-Based Proton Density Fat Fraction and T2* Maps in Patients with and without Osteoporosis.基于磁共振成像的质子密度脂肪分数和T2*图评估骨质疏松症患者和非骨质疏松症患者骨密度与椎骨髓和椎旁肌成分纵向变化之间的关联。
Diagnostics (Basel). 2022 Oct 12;12(10):2467. doi: 10.3390/diagnostics12102467.